ID A0A4D9EEI7_9SAUR Unreviewed; 321 AA.
AC A0A4D9EEI7;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN ORFNames=DR999_PMT11370 {ECO:0000313|EMBL:TFK05932.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK05932.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK05932.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK05932.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK05932.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK05932.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK05932.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK05932.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ADP-ribosyl cyclase family.
CC {ECO:0000256|ARBA:ARBA00005406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK05932.1}.
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DR EMBL; QXTE01000106; TFK05932.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9EEI7; -.
DR STRING; 55544.A0A4D9EEI7; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProt.
DR GO; GO:0050135; F:NAD(P)+ nucleosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0061809; F:NAD+ nucleotidase, cyclic ADP-ribose generating; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd04759; Rib_hydrolase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR003193; ADP-ribosyl_cyclase.
DR PANTHER; PTHR10912; ADP-RIBOSYL CYCLASE; 1.
DR PANTHER; PTHR10912:SF4; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 2; 1.
DR Pfam; PF02267; Rib_hydrolayse; 1.
DR SUPFAM; SSF52309; N-(deoxy)ribosyltransferase-like; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..321
FT /note="ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5020037402"
SQ SEQUENCE 321 AA; 36276 MW; A5B53C1BC0EB81A8 CRC64;
MMKSFFLSLL VGLLFSKDYV KPTEIDGKKK WKGEGTTPNL ESIVIGRCYE YIRIVNPSVG
EKNCTEIWEA FKKAFINKDP CNILPSDYEL FINLSLHTIP PNKSLFWENN HLLVTSYSDR
TRRYMPLCDT LIGSFGDFLN WCGQANDTGF NYDSCPNTEE CENNAVESFW KSASITYAKQ
SSGVIYIMLN GSAIGGAYPV KGFFADYEVP NFQKDRISRI EIWVMDDIGG PDLDSCGRGS
VQILEERLKT MGYDSTCIDN YKSVLLLKCL DYLNHSDCSI VSSAPSTQRG LVSPDRGGSW
SRLIYTIFVA FVFEICFNPL N
//
