ID A0A4D9EFT9_9SAUR Unreviewed; 419 AA.
AC A0A4D9EFT9;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Carboxypeptidase A6 {ECO:0000313|EMBL:TFK05294.1};
GN ORFNames=DR999_PMT12077 {ECO:0000313|EMBL:TFK05294.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK05294.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK05294.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK05294.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK05294.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK05294.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK05294.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK05294.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M14 family.
CC {ECO:0000256|ARBA:ARBA00005988}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK05294.1}.
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DR EMBL; QXTE01000117; TFK05294.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9EFT9; -.
DR STRING; 55544.A0A4D9EFT9; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.340; Metallocarboxypeptidase-like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR036990; M14A-like_propep.
DR InterPro; IPR003146; M14A_act_pep.
DR InterPro; IPR000834; Peptidase_M14.
DR PANTHER; PTHR11705:SF65; MAST CELL CARBOXYPEPTIDASE A; 1.
DR PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR Pfam; PF00246; Peptidase_M14; 1.
DR Pfam; PF02244; Propep_M14; 1.
DR PRINTS; PR00765; CRBOXYPTASEA.
DR SMART; SM00631; Zn_pept; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00132; CARBOXYPEPT_ZN_1; 1.
DR PROSITE; PS00133; CARBOXYPEPT_ZN_2; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645,
KW ECO:0000313|EMBL:TFK05294.1};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..419
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5020038078"
FT DOMAIN 168..190
FT /note="Peptidase M14 carboxypeptidase A"
FT /evidence="ECO:0000259|PROSITE:PS00132"
FT DOMAIN 306..316
FT /note="Peptidase M14 carboxypeptidase A"
FT /evidence="ECO:0000259|PROSITE:PS00133"
SQ SEQUENCE 419 AA; 48116 MW; 262FED5745932E12 CRC64;
MKSMVPLGLI VATFALTSSR CFDSAKVFRV KPQNEKQVNF LKYLASIKQL DFWHPDSAPH
IVTQMQVDFH VSAHQSRSVQ TLMEQNEIQY EILLHNLQEE IEKQFDGKRN FTSRHSYTKY
NDWDKIAAWT ARIAKIYPKL VSRIQIGNTF EKQPMYLLKV GKKSGRKKAI FMDCGIHARE
WISPAFCQWF VKQAASTYGK DKIMTHLLDS LNFYVLPVFN IDGYVWSWTQ DRMWRKNRSK
NSSTNCTGTD LNRNFAAAWG TTGFISDDPC DETYYGPAPE SEDETKAVAT FIRNHLSSIK
AYLNIHAYSQ MLLFPYGYTF HKAPNHDELT EVAKAAMEAL SSLYSTKYEY GASATLIYPT
SGSSVDWAYD QGIKYSFVFE LRDKGRYGFL LPESKIKSTC KETMLAVKSI ANYILSYAS
//
