ID A0A4D9EJA6_9SAUR Unreviewed; 555 AA.
AC A0A4D9EJA6;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=26S proteasome regulatory subunit 8 {ECO:0000256|ARBA:ARBA00040909};
DE AltName: Full=26S proteasome AAA-ATPase subunit RPT6 {ECO:0000256|ARBA:ARBA00041419};
DE AltName: Full=Proteasome 26S subunit ATPase 5 {ECO:0000256|ARBA:ARBA00042601};
GN ORFNames=DR999_PMT05967 {ECO:0000313|EMBL:TFK10569.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK10569.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK10569.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK10569.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK10569.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK10569.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK10569.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK10569.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK10569.1}.
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DR EMBL; QXTE01000039; TFK10569.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9EJA6; -.
DR STRING; 55544.A0A4D9EJA6; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF166; 26S PROTEASOME REGULATORY SUBUNIT 8; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703}.
FT DOMAIN 246..385
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 514..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..133
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 555 AA; 61455 MW; FCCF1809F524EC92 CRC64;
MLPGRWGWVP SPWPQGWPQR FSHPPAPVRF GFFACDGAAG SLESLGGSPE ANRAPAGTHF
VELGLLGAWW LQMEMDEGKG GTGLRQYYLS KIEELQLIVN EKSQNLRRLQ AQRNELNAKV
RLLREELQLL QEQGSYVGEV VRAMDKKKVL VKVHPEGKFV VDVDKNIDIN DVTPNCRVAL
RNDSYTLHKI LPNKVDPLVS LMMVEKVPDS TYEMIGGLDK QIKEIKEVIE LPVKHPELFE
ALGIAQPKGV LLYGPPGTGK TLLARAVAHH TDCTFIRVSG SELVQKFIGE GARMVRELFV
MAREHAPSII FMDEIDSIGS SRLEGGSGGD SEVQRTMLEL LNQLDGFEAT KNIKVIMATN
RIDILDSALL RPGRIDRKIE FPPPNEEARL DILKIHSRKM NLTRGINLRK IAELMPGASG
AEVKGVCTEA GMYALRERRV HVTQEDFEMA VAKVKSASRC PSSGWGRWLQ CTSRFKRPIA
GSSVPSGLLA MPLVQLDVAA LPPVSPLLEK WGSPSQGLKA GAIQSWRDRQ RPALFSPKGG
RGERQAEGMQ RNEGP
//
