ID A0A4D9EW11_9SAUR Unreviewed; 974 AA.
AC A0A4D9EW11;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Protein spinster-like protein 2 {ECO:0000313|EMBL:TFK13395.1};
GN ORFNames=DR999_PMT03355 {ECO:0000313|EMBL:TFK13395.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK13395.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK13395.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK13395.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK13395.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK13395.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK13395.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK13395.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK13395.1}.
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DR EMBL; QXTE01000016; TFK13395.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9EW11; -.
DR STRING; 55544.A0A4D9EW11; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000165; P:MAPK cascade; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06624; STKc_ASK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR046873; HisK-N-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR043969; MAP3K_PH.
DR InterPro; IPR025136; MAP3K_TRAF-bd.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR11584:SF391; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6; 1.
DR PANTHER; PTHR11584; SERINE/THREONINE PROTEIN KINASE; 1.
DR Pfam; PF19039; ASK_PH; 1.
DR Pfam; PF20302; HisK-N-like; 1.
DR Pfam; PF13281; MAP3K_TRAF_bd; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000297703}.
FT DOMAIN 395..653
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 656..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 881..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 952..974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 911..934
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 424
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 974 AA; 107449 MW; 164984C8C4749BB4 CRC64;
MYSGEQLSRE LANIQQRLDS VELLSLDIVM NLLLSYRDVQ DYDAIIRLVE TLQALPTCDV
AEQHNIRFHY TFALERRNQP GDREKALSVL LPVVERREGA APDLYCMCGR IYKDMFIGSG
FTDTEKRDQA SYWYSKAFDT EPSLHSGINS AVLLIAAGHQ FETSVQLRQI GVKLSCLLSN
KGSVEKMQHY WDVGFYLGSW ILANDVSKVI RASEKLYTLN APVWYLASVM ETFLLYKHFK
TCPEIRAPKQ EQADFWMGFL LASCQPFVST ECCPVLILEL NKVLQPAQLT VRNCEAEKSV
TLCHICPPEE RGISSWTFLA SSIRGISISK CDERCCFLYV LHTAEDFQLY FPTQHHCQWF
CKLIHSFVAE LAVGGEEVGD GLDEDLEYDY EYTETGDRVI LGKGTYGVVY AGRDLSNQVR
IAIKEIPERD SRYSQPLHEE IALHKRLRHR NIVQYLGSIS QDGFIKIFME EVPGGSLSSL
LRSKWGPLKD NEPTIVFYTK QILEGLRYLH DNQIVHRDIK GDNVLINTYS GVLKISDFGT
SKRLAGMRPC AETFTGTLQY MAPEIIDQGP RGYGKPADIW SLGCTIIEMA TGNPPFYELG
SPQAAMFKVG MFKMHPEVPD SMSGAAKAFI LRCFEVDPDQ RAPAAALLQE PFLTAPSRKK
ARSQAVPAAE GGTPGAASSP APAAEGASKA RNPSLPFQAP RTAAKADSSS SEVAQRSSYL
GAAEEPAGLD CSSSPAPEES GGMFLLKKDS ERRATLHQIL TEEQPSIVAA LQEAQSQSRE
GGRLSSEHIA QLVSCLKSYI RSPSRRQLSQ DLLGLQAPLQ AEGLSLHHVQ VPLFSFQDTV
KQLLRQHQIK PHWMFALDNL MGQAVQAAFT ILMTELRVKP PRLLGKGGSE EEVEEDPEAR
GAPPPLSQPS VGRGSVETPS SGVGSGTSTE LGFRTAPADS LPLLVQLSRL RAETGSLGRA
PPGAPAGGGG RPPR
//
