ID A0A4D9EXQ3_9SAUR Unreviewed; 751 AA.
AC A0A4D9EXQ3;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Disintegrin and metalloproteinase domain-containing protein 20 {ECO:0000313|EMBL:TFK15406.1};
GN ORFNames=DR999_PMT01173 {ECO:0000313|EMBL:TFK15406.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK15406.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK15406.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK15406.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK15406.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK15406.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK15406.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK15406.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK15406.1}.
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DR EMBL; QXTE01000005; TFK15406.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9EXQ3; -.
DR STRING; 55544.A0A4D9EXQ3; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd16513; RING-HC_LONFs_rpt1; 1.
DR CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327:SF41; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3; 1.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00464; LON; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51787; LON_N; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS00518; ZF_RING_1; 2.
DR PROSITE; PS50089; ZF_RING_2; 2.
PE 4: Predicted;
KW Integrin {ECO:0000313|EMBL:TFK15406.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 120..158
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 189..222
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 458..496
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 544..744
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
SQ SEQUENCE 751 AA; 84860 MW; 01D0CBE45C099BA5 CRC64;
MGSHPPRQLL LQFAAGAFQA QHLERAAELC GSQLQVDAPS LVPEWQVLLK RADALAYGGR
LHEAFQLYQL VSRHQQLRAE QLEKLVECLA QGIRLRERLP ACWGGGGSLL PPRDWDIFSC
RKCQGFLFEP VSLPCGHTFC KKCLERDRAT ESHCALCKEE GSLAAGQHLR VNVILSNLLA
KWFPGQVKAS QLRHEGNLLY KEKKLQAALQ KYNEAVSLAP NDHLLYSNRS QINSTLKSYE
DALHDAETAC RLQPYWSKGH LRKGQALANV GKIEESLREF LFCLALDFGN RTAKSEAQKL
LLSLFSPIPG NAQEHLPDIL QLLSPHSRLK GNLLNSVGSA DTSHNLQRLL KVNVEQKKSF
PAQEEQKMSD CGSLRKSIQM IESKKGCSED ENKHASAPQS ALLISEKCSL LKRKHCSEEM
RSAEVPCKLM KKGAIDAKGS SAGRRVPFEF VDPSDLDCSL CMRLFYEPVT TPCGHTFCLK
CLERCLDHNA KCPLCKEGLS ECLALRKYCK TVLMEELIAK YLPEELTERR KIYEEEIAEL
SNLNKNVPIF VCTMAYPTVP CPLHIFEPCY RLMIRRCMET GTKQFGMCIG DPVKGFADYG
CILEIRNVEF FADGRSVVDS IGKRRFKVIE HSQRDGYNTA DIEYIEDQKV QGENYAELLV
LHDSVYDQAY MWFNSLKQPL KSRILSHFGP MPAKDPDPQA SPNGPAWCWW VLAVLPLESR
AQLPFLAMKS LKDRLNGIRR VLTFMSRTRS R
//
