ID A0A4D9FCR7_9SAUR Unreviewed; 2019 AA.
AC A0A4D9FCR7;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ATP-binding cassette sub-family B member 7, mitochondrial {ECO:0000313|EMBL:TFK15630.1};
GN ORFNames=DR999_PMT00941 {ECO:0000313|EMBL:TFK15630.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK15630.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK15630.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK15630.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK15630.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK15630.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK15630.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK15630.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK15630.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QXTE01000004; TFK15630.1; -; Genomic_DNA.
DR STRING; 55544.A0A4D9FCR7; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR CDD; cd16972; Alpha_kinase_ChaK2_TRPM6; 1.
DR Gene3D; 3.20.200.10; MHCK/EF2 kinase; 1.
DR Gene3D; 1.20.5.1010; TRPM, tetramerisation domain; 1.
DR InterPro; IPR004166; a-kinase_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR029597; TRPM6_a-kinase_dom.
DR InterPro; IPR041491; TRPM_SLOG.
DR InterPro; IPR032415; TRPM_tetra.
DR InterPro; IPR037162; TRPM_tetra_sf.
DR PANTHER; PTHR13800:SF15; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 6; 1.
DR PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR Pfam; PF02816; Alpha_kinase; 1.
DR Pfam; PF18139; LSDAT_euk; 1.
DR Pfam; PF16519; TRPM_tetra; 1.
DR SMART; SM00811; Alpha_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51158; ALPHA_KINASE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:TFK15630.1};
KW Calcium {ECO:0000256|ARBA:ARBA00022568};
KW Calcium channel {ECO:0000256|ARBA:ARBA00022673};
KW Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00022568};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000313|EMBL:TFK15630.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022568}.
FT TRANSMEM 916..935
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 947..966
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 986..1004
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1011..1028
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1040..1064
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1085..1105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1750..1980
FT /note="Alpha-type protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS51158"
FT REGION 20..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1491..1514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1567..1589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1997..2019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1574..1588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2019 AA; 230935 MW; 90160504C792B29F CRC64;
MEMPAWRDLL FSQLGSVCRS SRRGGGWRHP GHEGLSEGDE HRDLQTCPDS QPPASRRKQD
EMKVPLKSQK SWIEGVFNKR ECAKVIPSSK DPHRCPAGCQ ICQNLIRCCC GRLIGDHPGI
DYSSPVYQPT RERENEEWSV QKHTHTSPTD SFGTINFQDG DHTYHAKYIR TSYDTKLDQL
LHLMVKEWQM ELPKLVISVH GGIQNFKLPS KVKQVFSKGL VKAAETTGAW IITEGINSGV
SRHVGDALKA HASQYLRKIC AIGIPPWGII ENQRDLIGKD VVCLYQTLSN PLSKLSTLNS
MHSHFILADD GTVGKYGNEM KLRRNLEKYL NLQKIHTRMG QGVPVVGLVV EGGPNVILMV
WEYVRDTPAV PVVVCEGTGR AADLLAFIHK HTADTGDLPP QLKEEISVMI QNTFNFGQKQ
SIHLFQMLME CMVHRESITI FDAESEEQQD IDLAILTALL KGTNMSASDQ LNLALAWNRL
DIAKKHILVC GQDWKVGSLE QAMLDALVMD RVDFVKLLIE HGVNLHRFLT ISRLEELYNT
KQGPTNLLLH HLVRDVKQSA LPLDYKISLI DIGLVIEYLI GGAYQSSYTR KHFRVLYNSL
YRKRKSVVSS FAQSLSHHSL CHNNQMGSRV ESAENTLHSQ FIRTAQPYKY KEKSTAFHKS
RKKSKDELSF LEDHESAGFI YPYNDLLVWA VLMKRQKMAM FFWQHGEEAM VKAVVACKLY
RAMAHEAKQS NMVDDTSEEL KKYSDEFGQL ALDVLDNAFK QNEQMAMKLL TSELKNWSNS
TCLKLAVSVG LRPFVSHTCT QMLLTDMWMG RLKMRKNSWF KVILSILLPP TILMLEFKSK
AEMSHVPQLQ DFHQFTWHHS DQSPSTIKDE LSLDYDAEKG PEKPDKSQTF SINSAHGSLP
RTRKVYEFYN APIVKFWFHT MAYLAFLMLF TYTVLVKMES RPSVQEWLVI IYIFTTAIEK
VREIFISEPG KFSQKVKVWI YEYWNFTDSI AIILFVTGFG LRWADPPVQT VGRLIYCLDI
IFWYARLLDF FAVNQHAGPY LMMIGKMYII MVNLLIAFFN NVYYDMKSIS NKLWKYNRYR
YIMTYYEKPW LPPPFIILSH IGLLINHICH HRPPNELDQE EGDVGLKLYL SDEDLKKLHE
FEEQCVERYF HEKNESLNSS DSERIRVTSE RVEEMFLLLK EVYEKVFYIK DSLLSLDSQL
GHLQDLSALT VDTLKVISAV DTLQVEEALL AETKHRACRK LPHSWNNAMY SKTLSSLECL
NDKNYNYYSV PPSLLRSLAR SQWSSECHSH IVETGDYKDV KIAGIQKKQE IESDTLTSGV
SSESKSTPGY GQFLLVPHQG AASTEEVHLN LSLPSTPAKY RRDELAAKQQ NNHGSTVLHQ
SLQSTNLTEK KAKNCQERQW DSIIQLPSEK DNGIVVEHSV SPQPSATDRE TLVPSHNPSE
ETRVGYVNWG FSVGDEKGVL CNEKRQQSCM HSTCNSDCNC TRGTPQHVQI KASKSFSYNS
DKSGYDSDTS EPEPMCQRST IFWINPLRRD WTFHKSSSFQ SRKGEKVGKT CKSKELSKSA
ELIPSVWTEA KQQNRDRQSQ KDKKKQKTLQ VPVITVDGCP QSTQMSSEPA ESCFLGEDKY
NKNWLTVSNF NQLSLERLSY MHQKMKNQET GRHSLQICDS LRQSQEDLSN SMIGTTRKNN
LSRNSSLRSS NGIDKISVSL KTPQDLHHHY SAVERNNLMR LAQTIPFTPV QFFAGEEVTI
YRLEESSPLN LDKSMSSWSQ RGMAAMIQVL SQEEMDGGLR RAMKVICTWS ENDVLKLGQV
FIVKSFLPEV VQTWQTIFQE GTVLHLCLRE IQQQRAAQKL IYTFNQLKPH SIPYTPRFLE
VFLIYCHSAN QWLTIEKYMT GEFCKYNNNN GDEISPSNLL EEMMLAFSHW TYEYTRGELL
VLDLQGVGEN LTDPSVIKPE GKQSGGMVFG PANLGEHAIK NFIAKHHCNS CCRKLKLPDM
RRNDYTPTRL NPAVKVETEA GAESAVATDD KPLENYTRL
//
