ID A0A4D9FFI6_9SAUR Unreviewed; 967 AA.
AC A0A4D9FFI6;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Cytochrome P450 4V2-like {ECO:0000313|EMBL:TFK16034.1};
GN ORFNames=DR999_PMT00447 {ECO:0000313|EMBL:TFK16034.1};
OS Platysternon megacephalum (big-headed turtle).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Platysternidae; Platysternon.
OX NCBI_TaxID=55544 {ECO:0000313|EMBL:TFK16034.1, ECO:0000313|Proteomes:UP000297703};
RN [1] {ECO:0000313|EMBL:TFK16034.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK16034.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK16034.1};
RA Gong S.;
RT "Draft genome of the big-headed turtle Platysternon megacephalum.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:TFK16034.1, ECO:0000313|Proteomes:UP000297703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DO16091913 {ECO:0000313|EMBL:TFK16034.1};
RC TISSUE=Muscle {ECO:0000313|EMBL:TFK16034.1};
RA Gong S.;
RT "The genome sequence of big-headed turtle.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the nesprin family.
CC {ECO:0000256|ARBA:ARBA00008619}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TFK16034.1}.
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DR EMBL; QXTE01000002; TFK16034.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4D9FFI6; -.
DR STRING; 55544.A0A4D9FFI6; -.
DR Proteomes; UP000297703; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR Gene3D; 1.20.58.60; -; 3.
DR InterPro; IPR012315; KASH.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR47535; MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G; 1.
DR PANTHER; PTHR47535:SF2; NESPRIN-3; 1.
DR Pfam; PF10541; KASH; 1.
DR Pfam; PF00435; Spectrin; 1.
DR SMART; SM01249; KASH; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 3.
DR PROSITE; PS51049; KASH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000297703};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00385};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TOPO_DOM 1..917
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT TRANSMEM 917..939
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TOPO_DOM 939..967
FT /note="Perinuclear space"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT DOMAIN 909..967
FT /note="KASH"
FT /evidence="ECO:0000259|PROSITE:PS51049"
FT COILED 295..404
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 967 AA; 111174 MW; D1377960B70D520F CRC64;
MTQQPQDEFN TSVENAEAWM KAIQERLRIN DNTKGPRSAL EARLRETEKI CALEPEGRLK
MDLVLMKADA LLCCISEEEK HEILSKLKDI KAMWEETAIY ITHCHSRIEW VWLHWSEYLK
AQDEFYAWIH NMKVTLEPDI ELQLGLKEKQ WQLSHSQVLL NDVLNQSVLL ERLLEEAASL
FNRIGDPSVD EDVQKKMKVE YEEIKAEAQC RVKLLEKITK EHEQYKTNVD QFQLWLNGVT
ERLNCCIGET TTLPADNGLK TLQNIAKDVK RGEKKFKCLE VQSTGVIQNT SPLGAGKMKD
ELEELRKALE KLKLICGEEE ERMHKILKSE SAYQSQARQL EAEVQEFRKM LQRLEDDVES
GEKPKSEEDL VALWRKYIAT RAALAAEESK VERLKAQLKE LFRFSQNIQP LSDSVVAAIR
EYQRVKGKTF KMSTGTETEL RQSFQNPLRE FQLWKPSAQR LLDSTANVAE PSLTHAFLLQ
IEACLAQSSQ FKEQLMMLQL KKDLLSSIFG EERAKSLLVE VTDTAKEREI LHKSLLQRRS
RLQSLVTEHK DFDAGFVPLQ KKLSAIRAKV DLENEPQPDL LGKETRLQRL QMIQEELAEF
IVQMEELENL VQSNPTHRHK MNQLSSDYQT LKRSLEIILA RTEKHVREHW TFNNKLSDLQ
RWITMIEQKL ESYQDASGER NTESRVADLE GLLAEFPGKE IQLHLVGAHG QLVIESSSPE
GAAHVHTEMN QLTESLRSLK KMTISLLSSM QPNTTVVDTG KNITIVGNTL TTGFAFGSSA
VTLKHSQANV SKEEENSHLL KLMKDFEQWL HVENDKLSKI LVTKPSSCEE VKAIHSKLKE
LQSRVPEGQC LFEDLRSLQT VVGTSEDVED LRYQWMLYKS KLKDSSSSLT PRSLEEPNGF
RKRRPGGMCP FLHRVCWAAL PLQILLLFLL LLAFLLPLVE ETHSCKLANN FARSFNLMLR
YEGPPPT
//
