ID A0A4E0PXE3_9EURY Unreviewed; 1160 AA.
AC A0A4E0PXE3;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 11.
DE RecName: Full=PKD domain-containing protein {ECO:0000259|PROSITE:PS50093};
GN ORFNames=CUN85_06165 {ECO:0000313|EMBL:TGC09412.1};
OS Methanolobus halotolerans.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX NCBI_TaxID=2052935 {ECO:0000313|EMBL:TGC09412.1, ECO:0000313|Proteomes:UP000297295};
RN [1] {ECO:0000313|EMBL:TGC09412.1, ECO:0000313|Proteomes:UP000297295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY-01 {ECO:0000313|EMBL:TGC09412.1,
RC ECO:0000313|Proteomes:UP000297295};
RA Shen Y., Huang H.-H., Lai M.-C., Chen S.-C.;
RT "Isolation and Characterization of Methanogenic Archaea from Saline
RT Meromictic Lake at Siberia.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TGC09412.1}.
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DR EMBL; PGGK01000005; TGC09412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4E0PXE3; -.
DR Proteomes; UP000297295; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.160.20.110; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR011493; GLUG.
DR InterPro; IPR022038; Ig-like_bact.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR Pfam; PF12245; Big_3_2; 1.
DR Pfam; PF07581; Glug; 1.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000297295};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1137..1155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 709..782
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 364..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1101..1126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1160 AA; 124514 MW; 7B935F886F0718AC CRC64;
MFSTNPNHIF TDFSCKVPIT KYSLILSFLC ILLMIAPASA FSGGGSGTEA DPYQISNVAE
LQNMSLDLSA NYTLINDIDA SDTVNWNTGD GFDPIGDSSN KFTGTFDGNE FIISNLTINR
SGERYVGLFG YTAGSFITNV SLEKTNVTGG DYHVGGLVGY NSGGSINKSY SMGNVTGTNY
VGGLVGTNRD GTINTSYSTG NVTGTDNVGG LVGENWDASI NQGYSTCNVD GDSDVGGLVG
WNEGSGVVTQ SYSTGSVTGS SDVGGLVGTN YGGSINTSYS TGTVAGNDDV GGLVGENNNY
IYQSYSTGTV NGSTDVGGLV GKNNDGSVNQ SYSTGTVSGS NYVGGLVGNN SDGSVVDQSY
WDIDTSGQAS SDEGDGRTTE NMTHPYNSHT TYLSWDFTDV WGIHGGINDG YPALLSLTNF
PPNVSITKPE ASSYISDIFF VNASVTDPNG DSYISSVYLN NTTGNIASYT DLPQDNYSVP
FDSTFLVDGI YNITWESYEN ETADGLSGFQ TINIHIDNTN PTLSVNDDTD EGNLSQDFVI
CNISFSDENL NSSTIAVYNA SGLVGSNVSS ISPHSVVFED LEEGKYQLNA TVSDKAGNVV
EMTTREIVLD TTSPSINQII APSEANTGDN ITIKLNATDN IGVETYNITV DGEEYRMEEN
SGNYTHNISI PASDSGTLVS SITYNCTFVD AAGNINSTDD VVIDVSILPV ADFSASLTRG
NTPLSVEFTD HSSGLVQTWN WDFGDGSTST DQNPSHVFGS GNFTVYLTVE NSNGTSSKEL
NVRAVDEPAY TVSPNEGALL SKYGDDMNFS INSTLYSSYE WFIDGTPLNG SGVTLYNNNT
DDSVHLSYCN VNTSQYIAQE DFFMDVYNIS AHVSNESIDR TDVFTWEWTV TNSSTEDADD
IDQIINTTPE VNTSGNESYV RFNTSNQISE KTGIECSIDF VSFNTSNETD GIQIKIEVLN
TSALNESDID FSKNSVYQYL DISFNNESLV NDGSKNRSIE FKVLNNVGGG SLIIDTVYLK
HKGTSGWQSY EPELIRNDFA YSYFIVRDIP GFSPFAVTAD YEYDSGTRSD DGIPAYLKLQ
MLQNRSQSTK EDMDDKTVVT LGSESDEDIV QEDTTSDSSE QTIGDVPISD EGDNGQVLFI
GIGVLVLFAI LVLAFRKKEN
//
