ID A0A4P1R833_LUPAN Unreviewed; 1202 AA.
AC A0A4P1R833;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=TanjilG_00761 {ECO:0000313|EMBL:OIW04201.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIW04201.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIW04201.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIW04201.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM007369; OIW04201.1; -; Genomic_DNA.
DR RefSeq; XP_019455953.1; XM_019600408.1.
DR AlphaFoldDB; A0A4P1R833; -.
DR STRING; 3871.A0A4P1R833; -.
DR GeneID; 109356841; -.
DR KEGG; lang:109356841; -.
DR OrthoDB; 53793at2759; -.
DR Proteomes; UP000188354; Chromosome LG09.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR PANTHER; PTHR18934:SF213; 3'-5' RNA HELICASE YTHDC2; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF01424; R3H; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51061; R3H; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 39..102
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT DOMAIN 210..386
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 557..731
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1152..1202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1009..1037
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1170..1202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1202 AA; 132203 MW; 8DEE4CA06F4CA665 CRC64;
MTRKRENRGG GRGGGGGGGG SGGGGGRGPI HRQNLKVDEL TRIRISKILE DFLASNDEVY
KFDANLSNQE RAWVHQVAQK MGLKSKSYGF GNDRRVSVQK MKKMVDTNNG FGSLPPFSFS
QEANQALGDL FTHYPPDGVN SWEAVGENVV TPEKIKQKKD DIFSRPSMTK AEIAKKVEAL
ATRITKAPNL RQITEDRSKL PIASFIDVIT STVESHQVVL ISGETGCGKT TQVPQYILDH
VWGKGEACKI VCTQPRRISA TSVSERISSE RGENIGENVG YKIRLESRGG RQSSIVLCTT
GVLLRVLVSK GSRGTKMGSA KDDISGITHI IMDEIHERDR YSDFMLAIIR DMLPSHPHLH
LILMSATIDA ARFSQYFGGC PVINVPGFTH PVKTFYLEDV LSIVKSRNDN HLDNTTLSNP
MNNHEPSEEE KLSIDEAIDL AWSNDEWDLL LELVSSEGTP KVFNYQHSLT GITPLMVFAG
KGRVGDMCLL LSFGADCHLV AKDGTTALEI AEKENQPEAA EILKKHMGSD SSNSMEEKKL
LDNYLSTINP ELVDVVLVEQ LIRKICFDSE EGGILVFLPG WDDINRTREK LLASSFFKNS
SKFVVISLHS MVPAMEQKKV FKRPPNGCRK IVLSTNIAET AITIDDIVYV IDTGRMKEKS
YDPYNNVSTL QSSWVSKASA RQREGRAGRC QPGICYHLYS KLRAASLPDF QIPEIRRMPI
EELCLQVKLL DPSCKIEEFL RKTLDPPVFE SIRNAIIVLQ DIGALTVDEK LTQLGEKLGL
LPVHPSTSKM LFFAILMNCL DPALTLACAS DYRDPFTLPM LPEEKKRAAA AKSELASLYG
GCGDQFAVVA AFECWGNAKK MGLESRFCSE YFVSSSAMNM LSGMRKQLQA ELIRNGFIPE
DVSRYSMNAY DSGVLHAVLV AGLYPNVGRF LPNKGGKRVL IETAGGDKVR LHNHSTNIKL
TFKKNLDHTL IVYDEITRGD GGMNIRNCAV VGPLPLLLHS TEIAVAPAND NDDGDEDEDD
EGSGDENEDE DEVETGDGME LDAKSSENCE DKFMSSPDSL VRIIMDRWVY FGSTAIDVAQ
LYCLRERLSA AILYKVTHPR STLPPILGAS MHALACVLSC DGCAGMPMMA DGVDKLTSMV
YATNLGQSAP TLTRRMGKKP KGPFTEHINK HQNPGPSSQV SISASKSIAN TSGINPKPSP
SK
//
