ID A0A4P1R989_LUPAN Unreviewed; 360 AA.
AC A0A4P1R989;
DT 03-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 03-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Cysteine proteinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=TanjilG_23458 {ECO:0000313|EMBL:OIW05672.1};
OS Lupinus angustifolius (Narrow-leaved blue lupine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC genistoids sensu lato; core genistoids; Genisteae; Lupinus.
OX NCBI_TaxID=3871 {ECO:0000313|EMBL:OIW05672.1, ECO:0000313|Proteomes:UP000188354};
RN [1] {ECO:0000313|EMBL:OIW05672.1, ECO:0000313|Proteomes:UP000188354}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. Tanjil {ECO:0000313|Proteomes:UP000188354};
RC TISSUE=Whole plant {ECO:0000313|EMBL:OIW05672.1};
RX PubMed=27557478; DOI=10.1111/pbi.12615;
RA Hane J.K., Ming Y., Kamphuis L.G., Nelson M.N., Garg G., Atkins C.A.,
RA Bayer P.E., Bravo A., Bringans S., Cannon S., Edwards D., Foley R.,
RA Gao L.L., Harrison M.J., Huang W., Hurgobin B., Li S., Liu C.W.,
RA McGrath A., Morahan G., Murray J., Weller J., Jian J., Singh K.B.;
RT "A comprehensive draft genome sequence for lupin (Lupinus angustifolius),
RT an emerging health food: insights into plant-microbe interactions and
RT legume evolution.";
RL Plant Biotechnol. J. 15:318-330(2017).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM007368; OIW05672.1; -; Genomic_DNA.
DR RefSeq; XP_019454205.1; XM_019598660.1.
DR AlphaFoldDB; A0A4P1R989; -.
DR STRING; 3871.A0A4P1R989; -.
DR GeneID; 109355475; -.
DR KEGG; lang:109355475; -.
DR OrthoDB; 1085298at2759; -.
DR Proteomes; UP000188354; Chromosome LG08.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF882; CYSTEINE PROTEASE RD19C-RELATED; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000188354};
KW Signal {ECO:0000256|SAM:SignalP};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..360
FT /note="Cysteine proteinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5020034800"
FT DOMAIN 45..101
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 128..353
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 360 AA; 39435 MW; E01B591EB9DECBC8 CRC64;
MNHSFFLSLS LSLLFVSVFS SDGADPLIRQ VIDGDDARLG AEDHFSAFKI RFGKTYSSEA
EHDYRFKVFN ANLRRAKRHQ NMDPSATHGV TRFSDLTPSE FRNSVLGLRR LRLPSDANKA
PILPTDNLPN DFDWRDHGAV TPVKNQGSCG SCWSFSTNGA LEGAHFLSTG ELVSLSEQQL
VDCDHECDPD EPGSCDSGCN GGLMNSAFEY ILKSGGVMRE KDYPYSGTDC GTCKFDKTKI
AASVANFSVV SLDENQIAAN LVKNGPLAVA INAVFMQTYI GGVSCPYICS KHLDHGVLLV
GYGSDAYAPI RMKEKPYWII KNSWGENWGE NGYYKICRGR NICGVDSMVS TVAAVHTSTT
//
