ID A0A4P6PAY2_9BACT Unreviewed; 302 AA.
AC A0A4P6PAY2;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Prephenate dehydrogenase/arogenate dehydrogenase family protein {ECO:0000313|EMBL:QBG46945.1};
GN ORFNames=EGM51_05885 {ECO:0000313|EMBL:QBG46945.1};
OS Verrucomicrobia bacterium S94.
OC Bacteria; Verrucomicrobiota.
OX NCBI_TaxID=2488809 {ECO:0000313|EMBL:QBG46945.1, ECO:0000313|Proteomes:UP000289135};
RN [1] {ECO:0000313|EMBL:QBG46945.1, ECO:0000313|Proteomes:UP000289135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S94 {ECO:0000313|EMBL:QBG46945.1,
RC ECO:0000313|Proteomes:UP000289135};
RA Baek K.;
RT "Verrucomicrobia bacterium S94.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP036201; QBG46945.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4P6PAY2; -.
DR KEGG; vbs:EGM51_05885; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000289135; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000289135};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..302
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 302 AA; 32583 MW; CEF8605ECEA32673 CRC64;
MHLFSSNEGY MNSKTNIAIL GLGLMGASLA LGLKKRGFRG CIKGYARREI TRVQALESGV
ADEVFADPEE AVRDADLVVI CVPIWTIAKL AEQIVPALKP GAVVTDVGST KSELLKLMCP
LFKASDAYFV GSHPIAGSEK TGIEAGNPDL YDGRLCIVCP VESTPAEADE RVSNLWKTAG
SEVVAMSPCE HDALLASTSH LPHMIAAALA RSVAGGDPAK KADYCGTGFK DTTRVASGSA
DMWVDIIDTN RDALVEEIDR FHDELQGLIK ILRSGNGNDI RKWLEEARNG RDEILKLNRF
LK
//
