ID A0A4P6Q6R9_9ACTN Unreviewed; 403 AA.
AC A0A4P6Q6R9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Phosphoserine phosphatase 1 {ECO:0000313|EMBL:QBI54759.1};
DE EC=3.1.3.3 {ECO:0000313|EMBL:QBI54759.1};
GN Name=pspA3 {ECO:0000313|EMBL:QBI54759.1};
GN ORFNames=EKD16_14905 {ECO:0000313|EMBL:QBI54759.1};
OS Streptomonospora litoralis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Streptomonospora.
OX NCBI_TaxID=2498135 {ECO:0000313|EMBL:QBI54759.1, ECO:0000313|Proteomes:UP000292235};
RN [1] {ECO:0000313|EMBL:QBI54759.1, ECO:0000313|Proteomes:UP000292235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M2 {ECO:0000313|EMBL:QBI54759.1,
RC ECO:0000313|Proteomes:UP000292235};
RA Khodamoradi S., Hahnke R.L., Kaempfer P., Schumann P., Rohde M.,
RA Steinert M., Luzhetskyy A., Wink J., Ruckert C.;
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP036455; QBI54759.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4P6Q6R9; -.
DR KEGG; strr:EKD16_14905; -.
DR OrthoDB; 5296884at2; -.
DR Proteomes; UP000292235; Chromosome.
DR GO; GO:0036424; F:L-phosphoserine phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR CDD; cd09279; RNase_HI_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR014636; RNaseH/PGlycerate_mutase.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR48100; BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED; 1.
DR PANTHER; PTHR48100:SF68; GLUCOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR PIRSF; PIRSF036922; RNaseH_PGAM; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:QBI54759.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000292235}.
FT DOMAIN 1..134
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 148..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 209
FT /note="Tele-phosphohistidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT ACT_SITE 282
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-1"
FT BINDING 258
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 403 AA; 41386 MW; 669871A34B0E79C5 CRC64;
MSRRLVIEAD GGSRGNPGPA GFGAVVRDAS TGELLAEVAE ALGVATNNVA EYRGLIAGLA
AAGGIAPGAA VEARMDSKLV VEQMSGRWRV KHAALKPLVE EARAKAADFA EVRYTWIPRA
DNSHADGLAN EAMDAAAEGR PVRIGAEGAD GAAQTAAEDA GTAGAPGGAA EPVGAVVPAG
GAGVRAEQPA ATGWAAPDTA PTRLILLRHG QTPMSVERRF AGAGDIGLTE TGHAQARAAA
RHLAAAGVDV VVSSPLRRAR DTADPIAAEL SLPVEEVGGL RETDFGAWEG LTFGEVQGSR
PGELQRWLSD IRAAPEGGES FAAVAERVAE AREKLLARHA GRTVLVVSHV TPIKVLLQQA
LLAPPEALFR MHLDVGCLSR IDCFSDGPML VRSLNDTGHL GSA
//
