ID A0A4P6TYQ1_STRSO Unreviewed; 459 AA.
AC A0A4P6TYQ1;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Insulinase family protein {ECO:0000313|EMBL:QBJ92630.1};
GN ORFNames=D0Z67_21615 {ECO:0000313|EMBL:QBJ92630.1};
OS Streptomyces seoulensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=73044 {ECO:0000313|EMBL:QBJ92630.1, ECO:0000313|Proteomes:UP000292547};
RN [1] {ECO:0000313|EMBL:QBJ92630.1, ECO:0000313|Proteomes:UP000292547}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 9819 {ECO:0000313|EMBL:QBJ92630.1,
RC ECO:0000313|Proteomes:UP000292547};
RA Shin J., Lee J.-S., Lee E.-J., Youn H.-D.;
RT "The complete genome sequence of Streptomyces seoulensis, a pioneer strain
RT for nickel superoxide dismutase discovery.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR EMBL; CP032229; QBJ92630.1; -; Genomic_DNA.
DR RefSeq; WP_031183473.1; NZ_JNXP01000028.1.
DR AlphaFoldDB; A0A4P6TYQ1; -.
DR STRING; 73044.GCA_000725795_05391; -.
DR KEGG; sseo:D0Z67_21615; -.
DR OrthoDB; 9811314at2; -.
DR Proteomes; UP000292547; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF149; GH01077P; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000292547}.
FT DOMAIN 45..192
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 199..380
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 459 AA; 49573 MW; 281003F4D0D1CE09 CRC64;
MTSRSFKATA RTSSEARAVA RTQTLIKGQD GIGTVRRTTL PGGLRIVTET LPSVRSATFG
IWAHVGSRDE TPALNGATHY LEHLLFKGTD KRSALDISAA VDAVGGEMNA FTAKEYTCYY
ARVLDTDLPL AIDVVCDMLT GSLIREEDVD VERGAILEEI AMTEDDAGDC VHDLFAHTMF
GDNALGRPVL GTVDTVNALT ADRIRRFYKK HYDPTHLVVA AAGNIDHATV VRQVRAAFEK
SGALRDNGAQ PIAPREGSRT IRTAGRVELV GRKTEQAHVI LGMPGLARTD DRRWAMSVLN
TALGGGMSSR LFQEVREKRG LAYSVYSYTS GFADCGLFGV YAGCRPSQVH DVLKICRDEL
DQVAANGLSD DEVNRAIGQL KGGTVLGLED TGALMNRIGK SELCWGDHMS VDDMLARITA
VTPDEVRSVA RDILGQRPSL SVIGPLKDKQ AARLNDAVA
//
