ID   A0A4P8IRW3_9BURK        Unreviewed;       986 AA.
AC   A0A4P8IRW3;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Formate dehydrogenase {ECO:0000313|EMBL:QCP48649.1};
GN   ORFNames=FAZ95_05255 {ECO:0000313|EMBL:QCP48649.1};
OS   Trinickia violacea.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Trinickia.
OX   NCBI_TaxID=2571746 {ECO:0000313|EMBL:QCP48649.1, ECO:0000313|Proteomes:UP000298656};
RN   [1] {ECO:0000313|EMBL:QCP48649.1, ECO:0000313|Proteomes:UP000298656}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DHOD12 {ECO:0000313|EMBL:QCP48649.1,
RC   ECO:0000313|Proteomes:UP000298656};
RA   Gao Z.-H., Qiu L.-H.;
RT   "Burkholderia sp. DHOD12, isolated from subtropical forest soil.";
RL   Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; CP040077; QCP48649.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4P8IRW3; -.
DR   OrthoDB; 9815647at2; -.
DR   Proteomes; UP000298656; Chromosome 1.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02783; MopB_CT_2; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.30.200.210; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR   PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          12..68
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
FT   REGION          430..460
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        438..452
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   986 AA;  109809 MW;  52A8A660C641A783 CRC64;
     MEHRARTQNE KLEVKTTTCY MCACRCGIRV HLRDGEVRYI DGNPNHPLNQ GVICAKGSSG
     IMKQYSPARL TQPLMRKPGA ERGTAQFEPV SWDVAFATLE KRLGHLRATD PKKFALFTGR
     DQMQALTGLF AKQFGTPNYA AHGGFCSVNM AAGMIYTMGG SFWEFGGPDL DSAKLFFMIG
     TAEDHHSNPL KIALSKFKRA GGRFIAINPV RTGYAAIADE WVPIRPGTDG ALFMALIREL
     IETESYDREF VTRYTNAAEL LDMNAERNTF GLFVQDPESP VGNPLFPQNR MWWDPAAQRA
     VVHHAPGVTP ALEGRYALAD GTPVVPSFAL LREQVAECTP EWASEITGIP ADTIRRLAQE
     MADTARDHKI TLPIPWTDAW GQTHDTVTGN PIAFHAMRGL AAHSNGFQSI RALSILMSIM
     GTIDRPGGFR HKSPYPRAVP PSAKPPNDPD VIQPNTPLAN GPLGWPAAPE DLFVDKDGQP
     GRIDKAFSWE YPLAVHGLMH SVITNAWRGD PYPIDTLFIF MANLAWNSSM NTVEVRKMLA
     DKHENGEHKI PFIVVCDAFQ SEMTAFADLI LPDTTYLERH DAMSVLDRPI SEYDGPVDSV
     RVPVVPPTGE CKPFQEVLIE LGSRLKLPAF TKEDGTRKYR DYPDFVVNFQ TSPNSGVGFL
     AGWRGKDGDK ALVGEPNPNQ WEQYAKNNCV FHFTLPESIQ YMRNCNGPYL KWAVENGFRK
     FDTPIVIQLY SDVLQKFRLA ARGKTTGRQP PDHLRARIER YFDPLPFYYP PLENAATDTA
     RYPLAAITQR PMAMYHSWDS QNAWLRQIHG ENYLFMNPRM AQENGIEDGG WIYVESQWGK
     VRCMARYSEA VEPGTVWTWN AIGKAAGAWN LGPDANESKH GFLLNHLITD ELPAQEKNAA
     AGARMSNSDP VTGQAAWYDV RVRVYPAEAD ADHTLPQFAP MTALPGSTGA NAVQRVVQAY
     FAGRGEFAKR LMQAVKPAAK HHDGEQ
//