ID   A0A4P8YI31_9ENTR        Unreviewed;       720 AA.
AC   A0A4P8YI31;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Formate dehydrogenase subunit alpha {ECO:0000313|EMBL:QCT20395.1};
GN   ORFNames=FEM41_12415 {ECO:0000313|EMBL:QCT20395.1};
OS   Jejubacter calystegiae.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Jejubacter.
OX   NCBI_TaxID=2579935 {ECO:0000313|EMBL:QCT20395.1, ECO:0000313|Proteomes:UP000302163};
RN   [1] {ECO:0000313|EMBL:QCT20395.1, ECO:0000313|Proteomes:UP000302163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSNA2 {ECO:0000313|EMBL:QCT20395.1,
RC   ECO:0000313|Proteomes:UP000302163};
RA   Jiang L., Jeong J.C., Kim C.Y., Kim D.H., Kim S.W., Lee j.;
RT   "Complete genome sequence of Izhakiella calystegiae KSNA2, an endophyte
RT   isolated from beach morning glory (Calystegia soldanella).";
RL   Submitted (MAY-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; CP040428; QCT20395.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4P8YI31; -.
DR   KEGG; izh:FEM41_12415; -.
DR   OrthoDB; 9810782at2; -.
DR   Proteomes; UP000302163; Chromosome.
DR   GO; GO:1990204; C:oxidoreductase complex; IEA:UniProt.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; IEA:UniProt.
DR   GO; GO:0015942; P:formate metabolic process; IEA:InterPro.
DR   CDD; cd02753; MopB_Formate-Dh-H; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 2.20.25.90; ADC-like domains; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR041924; Formate_Dh-H_N.
DR   InterPro; IPR006478; Formate_DH_asu.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR   NCBIfam; TIGR01591; Fdh-alpha; 1.
DR   PANTHER; PTHR43105:SF15; FORMATE DEHYDROGENASE H; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   PIRSF; PIRSF000144; CbbBc; 2.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR   PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000302163}.
FT   DOMAIN          1..56
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
SQ   SEQUENCE   720 AA;  79667 MW;  D5072224F74DF49C CRC64;
     MKKITSVCPY CGAGCKLKLV VDNNRITRVE AANGVTNQNE LCLKGYYGWD FLNDTRLLTP
     RLKQPMIRYR KDGPLEPVTW DEAIRYTAER LSDIKARYGS QAIMTTGSSR GTGNETNYVM
     QKFARAVLNT NNVDCCARVC HGPSVAGLQQ TLGNGAMSNA IADIENSRCL LIFGYNCADS
     HPIVARRVLK AKQRGARIIV CDPRKIETAR IADLHLQLNN GSNMALVNAF IHVLLEEELY
     DRAWVARHTE GLEALRETVK NYAPESVEGI TGVPAAAIRQ AMRLYCAAPS ATVMWGMGVT
     QFGQAVDVVK GLSSLALLTG NLGREHVGVG PVRGQNNVQG ACDMGVLPDH FPGYQRVDDP
     RTRAKFAAAW GVDPAAMDNK IGVRITDVPH LALEGKIKAY YIMGEDPLQT EADLGLVRRG
     IEALDLLIVQ DIFMTKTAEK ADVLLPATSW GEHGGIFTCA DRGFQRFEQA ITPRDDVRRD
     WQIISQIASA MGYPMHYDSN QQIWDEMREL CPLFYGATWE KIGEMGHLQW PCPTLEHPGT
     PWLYQGGRFD TPSGKGQLYA APWRPPAEQP DADYPLVLCT VREVGHYSCR SMTGNCAALQ
     TLADEPGFVA IHPQDAAPLG IKEDHLVRVA SRRGEVFSRA RLSERVNPGA VYMTYQWWIG
     ACNELTQDNM DPVSHTPETK YCAVRLLPIA DQDRAESEVL AAYSEMKARL RAAAEPVMQP
//