ID A0A4Q2K8L9_9FIRM Unreviewed; 693 AA.
AC A0A4Q2K8L9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN ORFNames=ESZ91_09415 {ECO:0000313|EMBL:RXZ58264.1};
OS Candidatus Borkfalkia ceftriaxoniphila.
OC Bacteria; Bacillota; Clostridia; Candidatus Borkfalkiales;
OC Candidatus Borkfalkiaceae; Candidatus Borkfalkia.
OX NCBI_TaxID=2508949 {ECO:0000313|EMBL:RXZ58264.1, ECO:0000313|Proteomes:UP000291269};
RN [1] {ECO:0000313|EMBL:RXZ58264.1, ECO:0000313|Proteomes:UP000291269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HDS1380 {ECO:0000313|EMBL:RXZ58264.1,
RC ECO:0000313|Proteomes:UP000291269};
RX PubMed=30658995;
RA Hildebrand F., Moitinho-Silva L., Blasche S., Jahn M.T., Gossmann T.I.,
RA Heuerta-Cepas J., Hercog R., Luetge M., Bahram M., Pryszlak A., Alves R.J.,
RA Waszak S.M., Zhu A., Ye L., Costea P.I., Aalvink S., Belzer C.,
RA Forslund S.K., Sunagawa S., Hentschel U., Merten C., Patil K.R., Benes V.,
RA Bork P.;
RT "Antibiotics-induced monodominance of a novel gut bacterial order.";
RL Gut 68:1781-1790(2019).
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RXZ58264.1}.
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DR EMBL; SDOZ01000003; RXZ58264.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Q2K8L9; -.
DR OrthoDB; 9807095at2; -.
DR Proteomes; UP000291269; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000291269}.
FT DOMAIN 61..150
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 155..585
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 693 AA; 76816 MW; 3C41ADBEF4D4A12C CRC64;
MKVPELFASN VFNRQIMQDK LPKEIYRSLL KTIDEGAPLD MSVANVVANA MKDWAVEKGA
THFTHWFQPM TGVTAEKHDS FISPTKDGKV IMEFSGKELV VGEPDASSFP SGGVRATFEA
RGYTAWDPTS FAFVKDGTLY IPTAFFSYSG EVLDKKTPLL KSMAALNEQA LRILRLFGNE
TVKRVYPTIG AEQEYFLIDR KMYDARKDLV FTGRTLFGAK APKGQELEDH YFGAIKTRVS
EYMKDLDEEL WKLGILAKTK HNEVAPSQHE LAPVFTSTNV ASDQNQLVME TMKKVAGRHG
LYCLLHEKPF AGINGSGKHN NWSMSTDTGM NLLDPGSTPA ENGQFMLFLT AVIKAVNEHQ
DLLRLSVASA GNDHRLGANE APPAIVSVFL GEELEAVIDS LERGVKYSDK GRKTMKLGVD
TLPELPKDTT DRNRTSPFAF TGNKFEFRMV GASLSLAGPN IIINTIVADA LRTFAEELEG
AKDFNAALHD LVVRELKENG RILFNGNNYS EEWAKEAARR GLLNLKNAAE ALPLFADKKN
IGLFERNGVF TAREVVTRTD IMLENYCKVL NIEALTMIEM AKRDIWPAVN EYIETLCNTA
RSKKEAGAAA AADRRLIQKL SADNDAMFER AEALEGLLVE GKACGTPALL AAFFAEKVIP
VMCELRMYAD GMELDTAAKV WPFPTYGDIL FSM
//
