ID A0A4Q4TUH5_9PEZI Unreviewed; 1282 AA.
AC A0A4Q4TUH5;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DL765_008081 {ECO:0000313|EMBL:RYP10512.1};
OS Monosporascus sp. GIB2.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Xylariales incertae sedis; Monosporascus.
OX NCBI_TaxID=2211647 {ECO:0000313|EMBL:RYP10512.1, ECO:0000313|Proteomes:UP000291414};
RN [1] {ECO:0000313|EMBL:RYP10512.1, ECO:0000313|Proteomes:UP000291414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GIB2 {ECO:0000313|EMBL:RYP10512.1,
RC ECO:0000313|Proteomes:UP000291414};
RA Robinson A.J., Natvig D.O.;
RT "Complete Genomes of Monosporascus.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RYP10512.1}.
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DR EMBL; QJNV01000287; RYP10512.1; -; Genomic_DNA.
DR STRING; 2211647.A0A4Q4TUH5; -.
DR Proteomes; UP000291414; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291414};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..490
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 502..589
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 599..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 840..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 892..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 952..1172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..860
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 961..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1052..1068
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1282 AA; 139432 MW; 27707CC79B7B6718 CRC64;
MAPGARSDKT GAMSSAMPGQ KTKLGVVSGV YLPVVLNIIS ILMFLRFGSI LGLIGLSGIL
AYFVDFITTL SLSAIASNGE VKGGGAYYLI SRSLGPEFGG SIGVLFYLSQ VLNTALNIVG
LIDCLKLNLG PLIPHGFWES YAMETCALVV CTALCLAGSA IFAKASNGLV VVLVIAALSI
PVSMVTRHPF SDPDLGVELT GPSLRTLSSN LYPHASGQAY RGLETFREMF GVLFAATSGI
FAGASMSGDL RNPSKAIPKG TLWAMLSTFI LYLVVILSMA SSITHASFVR HTNVIFTTSV
YSPLILAGEC ATTFFSALMG VVGAAKLLQA LARDKLLPGL AVFGQGTKRG DEPIFAVLLT
YGIAQLALFA DLNQIATFIS MGYQMTFFVM NLACFLLKIG SAPNFRPAFH FFSWETAFLG
SVLSAAAMFF IDETYAASAI SLLIFLFLLI HYTSPPKHWG DVSQNLIYHQ VRKYLLRLKP
EHIKFWRPQI ILLINDPRHH TRLIQFCNSM KKGALYILGH VIVTEDFISG IDEAKLQQSA
WSRYISEYSR IKAFVQLTMS PSIEWGVRNL ILSAGLGGMR PNIAVLGFYN MDELRRSWPR
GHVPDGPSTP TTPRAAQKAG GKPARRRRGD TSARLLEGFL PTDEMRTEGM LSPTSYMTIL
EDLALRHRLN VAVGIGFQAL ETPQRDGSNT KKFIDLWPIQ MSAEITSGEK SVLTSNFDTY
TLILQLGYIL FSVPAWKKAF RLRVLVFVEY ESEIEDERRR LKALLEKLRI EAQIVVFALA
SGQLSTYEYI VNGDTSRSDT AHIVNELLKD DEWWKELQRM RNEAAEISRS QELASLGAVL
EETKRRNSDP HLGEEDGSSR RFSVQDLLEL PKNPTVSRIS KLGVNFGIHT HRLSPVAFPD
PDQGDSAYSD DSDSESTSSS DADFNHAASL ANGYSSDESN LSRRQSLSAL TRHRKSVGDI
MMRQSTPTES APVMRNHPAR SRTTASSGYG TISSEPTQPT PERRPPSTPI DPPRRTASSM
PLLGTVAESG ETSAMGTAPP AAAPPRPPLS RHSSASRFTS NLTPDTKITV EEESGPKLQF
SEPGSSSAAA KTERPQLSRN SSMRKLSSRP VPETRVEDEE GAGPGLTLAG PEGEARTPRT
PLSRQNSVAR RGDGGGGVSE PTSSTGDVHL DIPELLESYR LSGTRHRSGE GDGSSYSTQG
LPLSFNDLPS RAQHLILNEL MRRNSGDGGA AVLLSTLPIP AEGTCRSEDD SLRYLSDIEV
LCHDLPPVLL VLSNNMTVTV SL
//
