ID A0A4Q7P4B4_9FIRM Unreviewed; 706 AA.
AC A0A4Q7P4B4;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=Glutamine synthetase {ECO:0000256|ARBA:ARBA00021364};
GN ORFNames=EV209_2340 {ECO:0000313|EMBL:RZS94497.1};
OS Cuneatibacter caecimuris.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Cuneatibacter.
OX NCBI_TaxID=1796618 {ECO:0000313|EMBL:RZS94497.1, ECO:0000313|Proteomes:UP000292927};
RN [1] {ECO:0000313|EMBL:RZS94497.1, ECO:0000313|Proteomes:UP000292927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 29486 {ECO:0000313|EMBL:RZS94497.1,
RC ECO:0000313|Proteomes:UP000292927};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZS94497.1}.
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DR EMBL; SGXF01000004; RZS94497.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4Q7P4B4; -.
DR OrthoDB; 9807095at2; -.
DR Proteomes; UP000292927; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000292927}.
FT DOMAIN 64..158
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 163..594
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 706 AA; 77431 MW; C918002FC23A7A12 CRC64;
MGMSNVSDIF GSNVFSDAVM RERLPKKVYA ELKKTIEGRE DLNPMVAEVV ANAMKEWALE
KGATHYSHWF QPMTGITAEK HDAFISAPHS DGKVLEEFSG KELIKGEPDA SSFPSGGLRA
TFEARGYTAW DCTSPAFVKE DAAGVILCIP TAFCSYTGEA LDKKTPLLRS MEALNAQALR
ILRLFGNTTS KRVTPSVGAE QEYFLVNREK YLQRKDLVFT GRTLFGAMPP KGQEMDDHYF
GAILERVGAY MKDVNEELWK LGVSAKTQHN EVAPAQHELA PIYSTANVAV DHNQLVMETL
KKVAMRHGLT CLLHEKPFKG VNGSGKHNNW SIVTDDGINM LDPGVTPHEN IQFLLVLACI
LKAVDIHADL LRESAADVGN EHRLGANEAP PAIISVFLGE QLEDVISQLI STGEATHSKQ
GGTLKTGVSS LPDLVKDATD RNRTSPFAFT GNKFEFRMVG SRDSIGEANV VLNAVVAEAF
AEAADILEKS EDFEMAVHDL IKEYLADHQR IIFNGNGYAE AWVEEAQRRG LPNIRSMVDA
IPALVTEKAV KLYERFGIYT SAELQSRAEI QYDTYAKAVN IEARTMIDMA GKQIIPAVIK
AVKALADSMA SVAAACPEAD VSVQKELLLE TSAYLSETKV ALAALQEAAS KASAVREENA
CQAAHMCHDL VMPAMEDLRA PVDHLEMIVD KSMWPMPSYG DLMFEV
//
