ID A0A4R0RRW0_9APHY Unreviewed; 427 AA.
AC A0A4R0RRW0;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 28-JUN-2023, entry version 9.
DE RecName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000256|HAMAP-Rule:MF_03012};
DE Short=eIF3m {ECO:0000256|HAMAP-Rule:MF_03012};
GN ORFNames=EIP91_005253 {ECO:0000313|EMBL:TCD70003.1};
OS Steccherinum ochraceum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Steccherinaceae; Steccherinum.
OX NCBI_TaxID=92696 {ECO:0000313|EMBL:TCD70003.1, ECO:0000313|Proteomes:UP000292702};
RN [1] {ECO:0000313|EMBL:TCD70003.1, ECO:0000313|Proteomes:UP000292702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LE-BIN_3174 {ECO:0000313|EMBL:TCD70003.1,
RC ECO:0000313|Proteomes:UP000292702};
RA Fedorova T.V., Glazunova O.A., Landesman E.O., Moiseenko K.V.,
RA Psurtseva N.V., Savinova O.S., Shakhova N.V., Tyazhelova T.V., Vasina D.V.;
RT "Genome assembly of Steccherinum ochraceum LE-BIN_3174, the white-rot
RT fungus of the Steccherinaceae family (The Residual Polyporoid clade,
RT Polyporales, Basidiomycota).";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex, which is involved in protein synthesis of a
CC specialized repertoire of mRNAs and, together with other initiation
CC factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S
CC ribosome. The eIF-3 complex specifically targets and initiates
CC translation of a subset of mRNAs involved in cell proliferation.
CC {ECO:0000256|HAMAP-Rule:MF_03012}.
CC -!- SUBUNIT: Component of the eukaryotic translation initiation factor 3
CC (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03012}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03012}.
CC -!- SIMILARITY: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
CC {ECO:0000256|ARBA:ARBA00008482}.
CC -!- SIMILARITY: Belongs to the eIF-3 subunit M family. {ECO:0000256|HAMAP-
CC Rule:MF_03012}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCD70003.1}.
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DR EMBL; RWJN01000029; TCD70003.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R0RRW0; -.
DR STRING; 92696.A0A4R0RRW0; -.
DR Proteomes; UP000292702; Unassembled WGS sequence.
DR GO; GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:UniProtKB-UniRule.
DR GO; GO:0071541; C:eukaryotic translation initiation factor 3 complex, eIF3m; IEA:UniProtKB-UniRule.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0001732; P:formation of cytoplasmic translation initiation complex; IEA:UniProtKB-UniRule.
DR HAMAP; MF_03012; eIF3m; 1.
DR InterPro; IPR045237; COPS7/eIF3m.
DR InterPro; IPR027528; eIF3m.
DR InterPro; IPR040750; eIF3m_C_helix.
DR InterPro; IPR000717; PCI_dom.
DR PANTHER; PTHR15350; COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17; 1.
DR PANTHER; PTHR15350:SF2; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M; 1.
DR Pfam; PF18005; eIF3m_C_helix; 1.
DR Pfam; PF01399; PCI; 1.
DR SMART; SM00088; PINT; 1.
DR PROSITE; PS50250; PCI; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03012};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540, ECO:0000256|HAMAP-
KW Rule:MF_03012};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917, ECO:0000256|HAMAP-
KW Rule:MF_03012}; Reference proteome {ECO:0000313|Proteomes:UP000292702}.
FT DOMAIN 182..365
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 400..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 47095 MW; 9A4ED8891DCDCD3A CRC64;
MAASDAISVF AEGTFEEQIL ELVNYLARPL PEEQRPGFLQ PFQDALVTGE GQTPLDQDNE
RRQQILSKVL EQVKDLGDGS EREIEGFFNL LLAHLLSLFP LDAPQTSQFV VGLLQTIVNS
NEPSGTKYRI LTNLYNTIPQ HCGLRLPVQR TLVEIASAND ELSYISLSTA VLEKWLSEWD
VTDEEKSKFI KVVVDAYTKA GDAEASYQYS IVYVRSLPTS TETAHGAALD LISTALRSPT
VFDFDPLFRL DAVVAAKSHE TFPLLQIFLN DGLSEYKAWE ASHSDLYTKF DLDKAQLERK
IRLLSLASLA FQNLGRDVSY SVLATALQVE QSDVERWVID AIRAGLVSGK LSQTSQTFHV
VRAKARVFER AQWESLEKRL AAWKAGLASV LEVVASTKKR NGADSSATSA APNGVEAAAQ
PAQEVAA
//
