ID A0A4R1BM42_9ACTN Unreviewed; 583 AA.
AC A0A4R1BM42;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=E0L93_05645 {ECO:0000313|EMBL:TCJ18474.1};
OS Rubrobacter taiwanensis.
OC Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales; Rubrobacteraceae;
OC Rubrobacter.
OX NCBI_TaxID=185139 {ECO:0000313|EMBL:TCJ18474.1, ECO:0000313|Proteomes:UP000295244};
RN [1] {ECO:0000313|EMBL:TCJ18474.1, ECO:0000313|Proteomes:UP000295244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Yellowstone {ECO:0000313|EMBL:TCJ18474.1,
RC ECO:0000313|Proteomes:UP000295244};
RA Freed S., Ramaley R.F., Kyndt J.A.;
RT "Whole genome sequence of a novel Rubrobacter taiwanensis strain, isolated
RT from Yellowstone National Park.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCJ18474.1}.
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DR EMBL; SKBU01000011; TCJ18474.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R1BM42; -.
DR OrthoDB; 5241402at2; -.
DR Proteomes; UP000295244; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR42878:SF7; BACTERIOPHYTOCHROME; 1.
DR PANTHER; PTHR42878; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000295244};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 65..286
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 350..564
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 323..350
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 583 AA; 64857 MW; 5A69D363A18F593C CRC64;
MAVAYAVLAG ALFLTGVAWY YVSQNARTQE QSRFDEAAQR TLQAVDRRMN TYVDAMFGTR
GLFAASRSVE RGEFRAYVRS LDLRRRYPGI QALGYARRVP AGGLEAHVES VREEGYEGYE
VRPGGRGESF PLVYVEPEDA ANRSMFLGRN MYAAGVHRAA MDRARDVNLP RASGKVAPGG
PAGGPGFMIY LPVYRNGAPV STVPERREAL QGYVVAVFRA RELLEDIFIQ QGDPSVDFKV
YDGAEFGEEY LLYDRGSTAG ADGTGPAPLF SQTSTLQVGG RLWILRFSTL PGFGTSPQEN
LPRLVLYSGL ALSLVLFGLT AMLARSRTQA ERARSELEEA NRELESFSYT VSHDLRAPLR
SINGFSSILQ EDYAGRLDEE GRDYLRRVSA ASQNMGRLID ALLDFSRLRN RKLRTERVDL
SGIARSIADE LARRRPERRV EFAIQPGVTA RGDPDLLRVA LENLLGNAFK FTGKQERARI
EFGVEDAGGA PIYFVRDNGP GFDMAYADKL FGAFQRLHKT DEFEGTGIGL ATVRRIVERH
GGEIRGVGAV GRGAAFYFTL DLDREKPSRR KQRFPRWFRR SGS
//
