ID A0A4R1DQ57_9ACTN Unreviewed; 759 AA.
AC A0A4R1DQ57;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=FdhF/YdeP family oxidoreductase {ECO:0000313|EMBL:TCJ45078.1};
GN ORFNames=E0500_19815 {ECO:0000313|EMBL:TCJ45078.1};
OS Streptomyces sp. KM273126.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2545247 {ECO:0000313|EMBL:TCJ45078.1, ECO:0000313|Proteomes:UP000294981};
RN [1] {ECO:0000313|EMBL:TCJ45078.1, ECO:0000313|Proteomes:UP000294981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KM273126 {ECO:0000313|EMBL:TCJ45078.1,
RC ECO:0000313|Proteomes:UP000294981};
RA Ng Z.Y., Tan G.Y.A.;
RT "Novel actinobacteria from marine sediment.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCJ45078.1}.
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DR EMBL; SJXB01000080; TCJ45078.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R1DQ57; -.
DR OrthoDB; 5287431at2; -.
DR Proteomes; UP000294981; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000294981}.
FT DOMAIN 120..491
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 642..749
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 759 AA; 83054 MW; C370CCE2FBDE430D CRC64;
MATKPPKGDP VQDAPQVAGP KHAAAGLPAV GHSLRIAQQQ MGVKRTALTL LRVNQKDGFD
CPGCAWPEPE HRHTAEFCEN GAKAVAEEAT LRRVTPEFFA AHTVADLATR SGYWLGQQGR
LTHPMYLPEG GEHYEPVSWD RAFDIVAEEL KALQSPDEAL FYTSGRTSNE AAFLYQLFAR
EFGTNNLPDC SNMCHESSGS ALSETLGVGK GSVLLDDLYK ADLIIVAGQN PGTNHPRMLS
ALEKAKANGA RIITVNPLPE AGMERFKNPQ TPQGMLKGAA LTDLFLQIRI GGDQALFRLL
NKLILATDGA VDEDFVREHT HGYEEFAEAA RAADWDETLT ATGLTQEEIN EALGMVLASQ
RTIVCWAMGL TQHKHSVPTI REVVNFLLLR GNIGRPGAGV CPVRGHSNVQ GDRTMGIFER
PAPAFLDALE KEFGFAPPRE HGYDVVRAIR AMRDDKAKVF FAMGGNFVSA SPDTEVTEAA
MRRAHLTVHV STKLNRSHAV TGARALVLPT LGRTERDLQG SGEQFVTVED SMGMVHASRG
RLEPASDHLL SETAIVCRLA RRVLGEDSRT PWEEFEKDYA TIRDRIARVV PGFDDFNARV
ARPEGFALPH APRDERRFPT GTGKANFTAA PVEYPELPAG RLLLQTLRSH DQYNTTIYGL
DDRYRGIRNG RRVVLVNPED AAELQVADGS YVDLVGEWKD GVERRAPGFR VVHYPTARGC
AAAYYPETNV LVPLDATADT SNTPASKSVV VRLEQSGTD
//
