ID A0A4R1EYB6_9GAMM Unreviewed; 972 AA.
AC A0A4R1EYB6;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Molybdopterin dinucleotide binding protein {ECO:0000313|EMBL:TCJ83011.1};
GN ORFNames=EV695_3749 {ECO:0000313|EMBL:TCJ83011.1};
OS Cocleimonas flava.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Thiotrichaceae; Cocleimonas.
OX NCBI_TaxID=634765 {ECO:0000313|EMBL:TCJ83011.1, ECO:0000313|Proteomes:UP000294887};
RN [1] {ECO:0000313|EMBL:TCJ83011.1, ECO:0000313|Proteomes:UP000294887}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24830 {ECO:0000313|EMBL:TCJ83011.1,
RC ECO:0000313|Proteomes:UP000294887};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCJ83011.1}.
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DR EMBL; SMFQ01000005; TCJ83011.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R1EYB6; -.
DR OrthoDB; 9810782at2; -.
DR Proteomes; UP000294887; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02783; MopB_CT_2; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 2.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000294887}.
FT DOMAIN 12..69
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 972 AA; 110060 MW; 86C42353A0358210 CRC64;
MKNIPVVVET EGVEVKTTTC YMCACRCGIK VTVKDGEVRY IQGNPNHPLN KGVLCAKGAS
GIMKQYSPAR LTKPLLRKPG TERGAGEFEE ISWDKAYGIM EERLGKLREE DPKKFALFTG
RDQMQALTGM FAKQFGTPNY AAHGGFCSVN MAAGMIYTIG GSFWEFGGPD LERSKLFFMI
GTAEDHHSNP MKVELSKFKR NGGRFIAINP VRTGYAAIAD EWVPIKPGTD GALLLAIIRE
IIKLGMYDRD FLVNYTNSAE LIDITTDSHN EGMFIRNDEP VEEGCFDPQN KYWWDRVKDE
AVAMRKEGVD PFLTGEFELE DGTPCKPAFQ LLKERVEAYT PEWAEGITGI DADTIRRLAH
EMGIVARDQK IELPIQWTDA WGKDHDKVIG NPVSFHSMRG LAAHSNGFQT IRALSILMTL
LGTIDRPGGF RHKAPFPRPI PPCPKPPTGW GDVKPNTPLN GMPLGWPAGP DDLFVDDDGE
AIRLDKGFSW EYPLSVHGLM HNAITNAWRG DPYPIDTLML FMANMAWNSS MNTTEVRKML
VDKDEEGEYK IPFIIVADAY HSETVDFGDL ILPDTSYLER HDAMSMLDRP ISEYDGPVDA
VRIPVLPPKG ECKPFQDVIV ELGSRLKLPT FTDENGKRKF KDYRDLVINF ETAPGSGIGF
LAGWRGKSGE KSMKGEPNPN QWEMYKKNDC VFHYEMPKSF QYMRNWNRGY LHWAQEHNMI
RYDEPINIHV YSEILQKFRL AAQGKTEGRQ PPDRLRKRVE TYFDPLPFHY EPLESQLTDT
QKYPLNALTQ RPMAMYHSWD SQNAWLRQIH THNYLFVSPI LGRNNGFEDG DWVWVESMHG
KVRCMCRFSE SLEPGTVWTW NAIGKASGSW GLDAKANESN KGFLLNHVIS EELPPHDAGD
HVSNSDPVTG QAGWYDVRVR VYKAGDNEAS HTLPRFDTVK PLPGMEKKRR NKWQGYVAGK
FRKTLGRSGG LK
//
