ID A0A4R1NR99_9GAMM Unreviewed; 301 AA.
AC A0A4R1NR99;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=4-hydroxy-tetrahydrodipicolinate synthase {ECO:0000313|EMBL:TCL07316.1};
GN ORFNames=EZJ58_5631 {ECO:0000313|EMBL:TCL07316.1};
OS Sodalis ligni.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Bruguierivoracaceae; Sodalis.
OX NCBI_TaxID=2697027 {ECO:0000313|EMBL:TCL07316.1, ECO:0000313|Proteomes:UP000294555};
RN [1] {ECO:0000313|EMBL:TCL07316.1, ECO:0000313|Proteomes:UP000294555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=159R {ECO:0000313|EMBL:TCL07316.1,
RC ECO:0000313|Proteomes:UP000294555};
RA Deangelis K.;
RT "Investigation of anaerobic lignin degradation for improved lignocellulosic
RT biofuels.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCL07316.1}.
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DR EMBL; SJOI01000001; TCL07316.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R1NR99; -.
DR OrthoDB; 199953at2; -.
DR Proteomes; UP000294555; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR InterPro; IPR020625; Schiff_base-form_aldolases_AS.
DR PANTHER; PTHR12128:SF28; 2-DEHYDRO-3-DEOXY-D-GLUCONATE ALDOLASE YAGE-RELATED; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00666; DHDPS_2; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000294555};
KW Schiff base {ECO:0000256|ARBA:ARBA00023270}.
FT ACT_SITE 137
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 166
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 211
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 301 AA; 33334 MW; 12A8E35DABB72A75 CRC64;
MPNPRFYGVI PPVPTLFTAD EQLDEASMAN LLDSLIASDV NGLFFLGSAG EFAHMSEALR
FQTAEFCVNY VNKRKPVLVG IAHSGTREAI RFGLHAQKIG ADGVVAVNPY YNPLSEENLY
LHYKHLADAL ELPILIYNFP GLTGQSIPVP IIRRLAESCE NIVGLKDTVD TLSHIRETIH
AVKPVRPDFA VFSGYDEYLF GTLILGGDGC IPASANFAPQ LTCGIYQAWQ RQDYAEAVRL
QQRLSFIPEL YNYDLPFYNV VKYAIQLVGV DVSVNALWPA SPLTDELKAK IKAALQRSEV
I
//
