ID A0A4R4DX30_9PROT Unreviewed; 781 AA.
AC A0A4R4DX30;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:TCZ65410.1};
GN Name=clpA {ECO:0000313|EMBL:TCZ65410.1};
GN ORFNames=EXY23_04360 {ECO:0000313|EMBL:TCZ65410.1};
OS Roseicella aquatilis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Roseicella.
OX NCBI_TaxID=2527868 {ECO:0000313|EMBL:TCZ65410.1, ECO:0000313|Proteomes:UP000295023};
RN [1] {ECO:0000313|EMBL:TCZ65410.1, ECO:0000313|Proteomes:UP000295023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NE82 {ECO:0000313|EMBL:TCZ65410.1,
RC ECO:0000313|Proteomes:UP000295023};
RA Zhao Y., Du Z.;
RT "Paracraurococcus aquatilis NE82 genome sequence.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TCZ65410.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SKBM01000003; TCZ65410.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R4DX30; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000295023; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0043335; P:protein unfolding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR013461; ClpA.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02639; ClpA; 1.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF111; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Hydrolase {ECO:0000313|EMBL:TCZ65410.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:TCZ65410.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000295023};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 144..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..781
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 781 AA; 86398 MW; 4983DB71D771771B CRC64;
MLSRNLEQTL HRALGLANER RHEYATLEHL LLALTDDTDA STVLRACGVD SEKLKRDLTE
FLDKDLAGLV TERAGDPKPT AGFQRVVQRA AIHVQSSGRD EVTGANVLVA LFSERESHAV
YFLQLQDMTR LDAVNFISHG IAKAPGRAQS RPVQGTPASP QNEEQEKEEK PSRGRGQDAL
SNYCVNLNKK AQQGKIDPLI GRDSEIERTI QILCRRTKNN PLYVGDPGVG KTAIAEGLAK
RIIEGDVPEV LLKSTIFALD MGSLLAGTRY RGDFEERLKA VVSELEQQPG SILFIDEIHT
VIGAGATSGG AMDASNLLKP ALAQGTLRCI GSTTYKEYRN YFEKDRALVR RFQKIDVNEP
NLEDAVKILQ GLKTNYEKHH KVRYTPEAIR AAVELSAKYI HDRKLPDKAI DVIDEVGASR
MLLPENKRRK TVTLKDVEEI VAKIARIPPK TVSNDDKETL KTLERDLKSM VFGQEKAIET
LSAAIKLSRA GLRDPEKPIG NYLFSGPTGV GKTEVAKQLA KTLGIELIRF DMSEYMERHS
VSRLIGAPPG YVGFDQGGLL TDAIDQHPHA VLLLDEIEKA HQDLYNILLQ VMDHGKLTDH
NGKTVDFRNV ILIMTTNAGA ADLAKPAIGF GREQRVGEDQ EAIQRMFTPE FRNRLDAVVP
FSGLTPEIVG RVVEKFVMQL EAQLADRNVT IELSSAAKEW LAEKGFDPLY GARPLARIIQ
EYVKKPLAEE LLFGRLVKGG SVKVNLKDGE LAFDYVEAAA PALPRPEEGD GEPEKEPEVV
E
//
