ID   A0A4R4LIU5_9ACTN        Unreviewed;       305 AA.
AC   A0A4R4LIU5;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   28-JUN-2023, entry version 22.
DE   SubName: Full=Prephenate dehydrogenase/arogenate dehydrogenase family protein {ECO:0000313|EMBL:TDB79431.1};
GN   ORFNames=E1264_35525 {ECO:0000313|EMBL:TDB79431.1};
OS   Actinomadura sp. KC216.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2530370 {ECO:0000313|EMBL:TDB79431.1, ECO:0000313|Proteomes:UP000294687};
RN   [1] {ECO:0000313|EMBL:TDB79431.1, ECO:0000313|Proteomes:UP000294687}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KC216 {ECO:0000313|EMBL:TDB79431.1,
RC   ECO:0000313|Proteomes:UP000294687};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequences of novel Actinobacteria.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TDB79431.1}.
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DR   EMBL; SMJX01000328; TDB79431.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4R4LIU5; -.
DR   OrthoDB; 4149052at2; -.
DR   Proteomes; UP000294687; Unassembled WGS sequence.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          6..284
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   305 AA;  31681 MW;  5932C9B17E6F7036 CRC64;
     MSTPCFPRAV VAGAAGGFGR AFRALLAAHG SVVTGTDRLP PEGPGDHWFV ADAAAPPPAL
     LTELSRTDVL VLCLPEAALY PALEPLVGAL PAGALVVDTT SVKSRYAAIA AGIRPDVELL
     SLEPMFAPDV GFAGQHVIAI PLRDGPRTAA FRPLLQSTGA QVTELSADEH DRHAAAAQVA
     VHAALLAYAA TLRRPGHHGP GGPSTPPQRA LMALLARIVT RDPGTYWHIQ RDNPYGAEAR
     AVVRDALTAL DETVARNDRG GFDALLADTA AAFGPDLAPM VELSDEIVRS ARAHKELSQA
     AGDAP
//