ID   A0A4R4S9G9_9ACTN        Unreviewed;       458 AA.
AC   A0A4R4S9G9;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Insulinase family protein {ECO:0000313|EMBL:TDC59710.1};
GN   ORFNames=E1200_31695 {ECO:0000313|EMBL:TDC59710.1};
OS   Actinomadura sp. GC306.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2530367 {ECO:0000313|EMBL:TDC59710.1, ECO:0000313|Proteomes:UP000295346};
RN   [1] {ECO:0000313|EMBL:TDC59710.1, ECO:0000313|Proteomes:UP000295346}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GC306 {ECO:0000313|EMBL:TDC59710.1,
RC   ECO:0000313|Proteomes:UP000295346};
RA   Sahin N., Ay H., Saygin H.;
RT   "Draft genome sequences of novel Actinobacteria.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TDC59710.1}.
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DR   EMBL; SMKM01000404; TDC59710.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4R4S9G9; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000295346; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   4: Predicted;
FT   DOMAIN          44..166
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          197..363
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   458 AA;  47771 MW;  0B9D5DE88BDC5BF1 CRC64;
     MTSGLELQPR PVPGPVPAWT FPAGTEGRVP AGPATLRCDL PGRRLAAVRL VLHAGAGREP
     VLPDGRRLDG VATLAAHALT EGTEPGGGTA LTAAFERLGA SFFAHADLTA LRIALDVPTT
     RLGAAMELFA EVVRRPALDD GDVRRLVRER LEEIAQEDAD PGSRAMRELR AVMFPAEARA
     SRPTGGDRTS VEALQGADVR SFYGSVVPAE ATAVVAGDLS GTDADGALTA ALSGWAATGE
     PLPTADRVMP DSAARIVVVD RPGSVQTYLS FGHGVPDRSH HDWPSLTVAA HVLGGGLTSR
     LNAKLREEKG YTYGMRAGLL RMRHCGLFIA QGAVHTEVTA DAVSDALTEL RGIVSEGIGA
     DEHGSSVRAL ADRAPAEYET ARAVAAELAD VSANGLGTDY PSAYLAAVRA STPDGVARTY
     REHVDPEGLT VIAVGDAEQI RGPLEKLGYA TVTVTAKE
//