ID A0A4R5XFI9_9AGAM Unreviewed; 2749 AA.
AC A0A4R5XFI9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 08-NOV-2023, entry version 15.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
DE Flags: Fragment;
GN ORFNames=BD410DRAFT_780416 {ECO:0000313|EMBL:TDL29911.1};
OS Rickenella mellea.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Hymenochaetales; Rickenellaceae; Rickenella.
OX NCBI_TaxID=50990 {ECO:0000313|EMBL:TDL29911.1, ECO:0000313|Proteomes:UP000294933};
RN [1] {ECO:0000313|EMBL:TDL29911.1, ECO:0000313|Proteomes:UP000294933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SZMC22713 {ECO:0000313|EMBL:TDL29911.1,
RC ECO:0000313|Proteomes:UP000294933};
RG DOE Joint Genome Institute;
RA Krizsan K., Almasi E., Merenyi Z., Sahu N., Viragh M., Koszo T., Mondo S.,
RA Kiss B., Balint B., Kues U., Barry K., Hegedus J.C., Henrissat B.,
RA Johnson J., Lipzen A., Ohm R., Nagy I., Pangilinan J., Yan J., Xiong Y.,
RA Grigoriev I.V., Hibbett D.S., Nagy L.G.;
RT "A transcriptomic atlas of mushroom development highlights an independent
RT origin of complex multicellularity.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; ML170156; TDL29911.1; -; Genomic_DNA.
DR STRING; 50990.A0A4R5XFI9; -.
DR VEuPathDB; FungiDB:BD410DRAFT_780416; -.
DR Proteomes; UP000294933; Unassembled WGS sequence.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR039360; Ras_GTPase.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR10194:SF142; NEUROFIBROMIN; 1.
DR PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00616; RasGAP; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000294933}.
FT DOMAIN 1371..1564
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 2749
FT /evidence="ECO:0000313|EMBL:TDL29911.1"
SQ SEQUENCE 2749 AA; 305065 MW; E354915102297C29 CRC64;
MSGSGAAKGM MRRASSSSAH ASVATSVTRV HRSNDSHHGF VGTHPTHAGL PTLNAAASTS
SPQDKVVVAL IKRLTSKLPC YSGLTLAEIE SDDTIELAIQ SLAELARHAL DKIVWKLSEE
LEKLARQTDS NGYRAMDVLQ SQLFLLKVMS VTMSNHWQHN KAESSRLQSA SESTSGHGHS
NGTTPTSPTH PISSLKGATP RQYMTQASYD RSSPASLWLE APPLDEACAK WLISLVVHLL
RQATPRDSRS MWYGNLNFDA TLFGFESVES ENGNDCQEML YVFPPEPPEM MKPHPPPQRG
PRKHPSLTSM ASAMTASIPI PRSTQTFRAT ARTLTSSSLS LHSLVGKWAG NIVYLLSASN
WSVVFSRIRH KIRGLSQPSS EESVDIVDLQ LMQYCAFDRG RLIQMMQELS SLLVNMSRDA
QAAVAMALRK AIWNWIDNFP NEYNDVVNGS RRLDGAPERL FDLFFQISEA GNKSAIWPAM
SLLMVTSHDR LKGIAMMSSP AIGANKANKK ECQYKDQIAK NMNPASKLLD IALLASIDMC
RAASRARPEG DVVLRSIAPE VGDDIKGVLW KAHNQRPFYE SPDSIDVALF ADAMVAMFRF
LPEDESMHMF TACLEPERSD AVKMCAVKAC VILAQEAPRF PWQPTMKTIL RRIAPRLRNI
YRSAVLRRNE VDDMGNIKRA MPRPNAKRYT GETIADRELL VLGILALYRI DPRFYIPEKA
DMEDWVSDTV QVLLRPGDPA APLSSVRTFM QASRWVLDLR PGDEYFEEGT SWIGKAIPSA
LLCASTRLLD ARDDFDEQRM CIEMACGILS LYALGHADDD NRNSWRLAPD RIPAVAVAEL
AFLVSLTSAD NGVSTMATKG LRGIAILERH PNAPINPGLS EEERLMRHPI YEQLGDPKVM
AVGRVGHQRR LRKLLRSLAF PCPMHAAVWL ECYWRWSALE ESVSRRSIDG LSSEGTMNGQ
RPIGDRTMSP EERLFQWQNL TLFLAAFGAA GASEDLNSHL LTSIIPANHL PDRFRVLQDG
DEIIKNFITS AVDFLIADSV HARDCAKEAL GAELSPRLYS RLFKRLNDVI EDIMQTSKDS
EGETPEPEEE ELFLVFFEQF VAVLKLAVDR VDSLAESVFD NVDLGQTLLS LAKFIDRFTA
ASSLRVKVKF CAFCDSALAR SDSFGLRRDD KLRQSLLEAI VEWIQPSTSP NEESGSLGRF
LYEANMSGLK TVVKLLEGLR LQSLEGGSPD DAAHSISRRF SRYQSLLMQA LSSARPDDPL
TADDASVHST SSNRKDRVAE MRELVITGLT HLLSSNTDVG FKHCLQLGYD ADPIRRLVFC
HVIARVLWLG GKFDVVNHPT MLVRRSRLCE LVKGSDMTLA LAICETCPPS DTDILIPVML
NLFDSRASLM SLLKLIIEKE VRTAPNEVAL FRGNSMRTLL LCAFAKLHGY DYLRSVLKPL
IDQMCALPDD CSFELDPAKA LPGQDIKKNQ ETVKFVTQAF LDIICSSVSA LPPMIREICI
HISKTVADVW HEAKFSALGA FIFLRFISPT MVSPDTVDIE IPRNNVTIRR GLLIVTKIIQ
NLANNILFGK EAHMMVFNEF LSENIVRITR FLSDLNKYTP TDDEPEEWLG GTFDESDAIV
LHRFFEKHAD KVGKELLGLS MPSSQGEPAA TGGKRSWDAL CGALVEMGLP TGVPHLSPLS
SAEFSEYLSF MARTSDRSID PVRNLFWMAT SSKDMVNFVL DIRKFDVEVL DFELLLYHIF
KTVTSPDQES RPFSIVIDST GFTTASEIPI QWFKFAVELL PSDIKDRFKA FHILNANILM
QRYLRKLYNV CAGLYLSSDI RAYHSVKELG QRINGDIAST LEYASHLEQE QGDVFSDLTL
RQAQLMKMRV DVKIAQTYIR ITSVKAQVIF PNLAGKITEI VPLSDVDDIY NVTTGRDANE
FIVRRSRNGG TLYFASPERE QIIKAIRLAK GRLKTPMTVA LSRNPKLSNV SATLLNIGMN
NTMHQHSELR HAAHDLLSAV CLYIEYDGSP STQSRARIAP AYSTTSVVLL SERLAAFMPK
LTLDFLSEAC LSLESNPVSQ RINSLHYISP WIRNLGYFCD PASKYYEHSG AKLRDCVRLL
IDITMRDQQA YSSIQKHIWS EVAKLDHMLV NIVLDELMRA AVDGGVGSRR CDIMADTLAS
LSSINVRGRL ISRLRKTLGK ASVKPTKSLA DNAHWGEIAV FTRLALVTGY HSRQTTFNQL
FFPEIIHLAT LLAGTGETVV RHSVYGLVMN LLQSMGSSRG DELPSDIRNL IDDFTQPETL
HLFGLTRTFA ASEYSNYDPT NDQQAIDMLE GLSRLLLRAV NVCAGNGGLA NVWRARWMSL
LTATAFQLSL AIQPRAFIVM GTLAPSDVDD DLLYQMLVAL KSAMKVSDES DTTCVVSMLR
CICNLVHALP ENSRYLPQVF WLSVALLQSS HAAFYMEATS LLCASLHTLH AQGLLQERGF
TATLLDARAP LEEISIQLDR LLGVSFESSF SFSLASVIFK GMRRPQLREH AAAALNCLLT
TALSTSEISG SSDGTVHPDI LGYFLALLPV STTLQSYQQL LTDAGVGQDW FLADEATGRM
EGENGQVPRV AFDLLGCVDA NTALLVTSFV ATMLSTAQGD DVESQMLFTL LSDAASAFPE
TVSLSYEGLQ EKIYDTFASS TNPNILSAVS TIFRGAMEDP IRGIASKGSA STLSTVEESS
AFGPGRRHLL ALEELSMQGI ASTFQFLPLN RGHATKMLQW FPEIIARII
//
