ID   A0A4R6K514_9ACTN        Unreviewed;      1118 AA.
AC   A0A4R6K514;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=PKD repeat protein {ECO:0000313|EMBL:TDO43351.1};
GN   ORFNames=EV643_11893 {ECO:0000313|EMBL:TDO43351.1};
OS   Kribbella sp. VKM Ac-2527.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Kribbellaceae; Kribbella.
OX   NCBI_TaxID=2512215 {ECO:0000313|EMBL:TDO43351.1, ECO:0000313|Proteomes:UP000295388};
RN   [1] {ECO:0000313|EMBL:TDO43351.1, ECO:0000313|Proteomes:UP000295388}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM Ac-2527 {ECO:0000313|EMBL:TDO43351.1,
RC   ECO:0000313|Proteomes:UP000295388};
RA   Whitman W.;
RT   "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT   soil and plant-associated and newly described type strains.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TDO43351.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; SNWQ01000018; TDO43351.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4R6K514; -.
DR   OrthoDB; 9802683at2; -.
DR   Proteomes; UP000295388; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR   CDD; cd00146; PKD; 3.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   PANTHER; PTHR46730:SF1; PLAT DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46730; POLYCYSTIN-1; 1.
DR   Pfam; PF18911; PKD_4; 3.
DR   SMART; SM00089; PKD; 3.
DR   SUPFAM; SSF49299; PKD domain; 3.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   PROSITE; PS50093; PKD; 3.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000295388};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..1118
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038421491"
FT   DOMAIN          672..739
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   DOMAIN          756..823
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   DOMAIN          825..906
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
SQ   SEQUENCE   1118 AA;  114762 MW;  591C0A41D0061525 CRC64;
     MRKSVVCLFT ALLTALAGWL VVLGPSADAV QVSQDRVVSD DPANWTPHVL NGSVKSIQQF
     GDMIMIGGDF TQVSNRDGTI IYPRTNLAAF NATTGEVSDA FAPNPDGEVA AIIPAGDGTT
     AYVGGSFNNI SGGGSASLAR IDVTTGARIG GFKPAKLTGG RIKDLRLAGG RLWIAGMFAT
     VAGIAQPALA TLNPATGAHD PYMALPIAGL HNGGVTTVLK MDVTPDGSEL VAIGNFDTIA
     GVKHHQAFML NLTGASAAVE NWQTNFYNTA CSASFQTYMR DLDISPDGSY FVISTTGAYG
     GSLTACDSTA RFNTDARGSA LTPKWINNTG GDTTYAVAIT GSVVYTGGHA RWQNNPFSAD
     NAGQGAVSRP GIAALDPING LPLSWNPTRD RGVGVFDLLA TPTGLWVGSD TDRIGASEYH
     ARIAFFPIST GTVIQPNNTP TLPNNLYVAG RRSGTLFITW DNTINRSSFN GTTATALASV
     PNGGINWGNN RGAFMLNGQL YAGWSDGSFN RRSFDGTTVG ASTPVNTGDL LVNMSTWHNE
     VQGITGMFFD SGRIYFTRSG NSNLFYRYFT PESGVVGANI FTATGSLSGI SFNQMNGMFL
     AGNTLYWGQS TDGSLRKATW NPATGLPVSG TAQTLSTGID WRARTLFLYQ DPTGQGPNQL
     PTAQSAISCN DLNCSYSSAG SADPDGTIAS YAWTFGDGGT STDASPTHHY AAAGTYSVGL
     TVTDNRGGTN TITKNVVVTH VNTLPTATFG ETCDSLTCAF DGSGSTDPDG PIASYAWNFG
     DSTTGSGATP SHTYAASGTY TVSLTVTDNE GGTNTTSHPV TVTRVNQAPT ASFTTDCTDL
     ACTTDGSASA DPDGTLTGYA WDFGDGGTGT GATASHTYAA AGTYTIGLTV TDNDGATAST
     TRTVSVVDPA LAIEFVGSSR TNANASTFNV TVPAAVNAGD ALLLFFGDND PAPTITGPAG
     WTLVETVASS GQAARLWRKT ATAADAGSTV TVTTSALTKA DLTLLAYRGT AANPIANSAT
     GSETVSQTAH TTPTLSTSTV GGKLVSYWAE KSSLTTALTA PAGTTVRASG TGTGSGRTTS
     LAVETNDPVV PGTVGGLTAT ADSASARVLM FTVVLAAG
//