ID   A0A4R6NBQ8_9BURK        Unreviewed;       297 AA.
AC   A0A4R6NBQ8;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:TDP12094.1};
GN   ORFNames=DFR39_102482 {ECO:0000313|EMBL:TDP12094.1};
OS   Roseateles asaccharophilus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Sphaerotilaceae; Roseateles.
OX   NCBI_TaxID=582607 {ECO:0000313|EMBL:TDP12094.1, ECO:0000313|Proteomes:UP000295357};
RN   [1] {ECO:0000313|EMBL:TDP12094.1, ECO:0000313|Proteomes:UP000295357}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25082 {ECO:0000313|EMBL:TDP12094.1,
RC   ECO:0000313|Proteomes:UP000295357};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TDP12094.1}.
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DR   EMBL; SNXE01000002; TDP12094.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4R6NBQ8; -.
DR   OrthoDB; 9809920at2; -.
DR   Proteomes; UP000295357; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000295357}.
FT   DOMAIN          3..292
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   297 AA;  31557 MW;  5E39EBCBEC22F198 CRC64;
     MFNQLGVIGC GLMGGSFALA LKKAGLVKRV VGYSKSPSTT ETARRLGVID VAAESALLAV
     SGSDIVLLAV PVAATESTLR AVRHLVDPKV LFMDVGSTKC DVVEAARRAL GKQHLPAFVP
     AHPIAGKESA GVQHADAALY QGRQVILTPL AETHAPLVQK ATDVWSALGA QVLKMTPENH
     DQAFAAVSHL PHLLAFAYFQ AVASQPAGRD FLSLAGPGFR DFTRIAASDP AVWRDILTAN
     KTEVLLQSRL FRQALDALEA MMQGGDAAAL EARIRLISEA RSNWHMNVPR GGSRKDS
//