ID A0A4R6QGN1_9BURK Unreviewed; 716 AA.
AC A0A4R6QGN1;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DES47_11247 {ECO:0000313|EMBL:TDP61498.1};
OS Roseateles toxinivorans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=270368 {ECO:0000313|EMBL:TDP61498.1, ECO:0000313|Proteomes:UP000295361};
RN [1] {ECO:0000313|EMBL:TDP61498.1, ECO:0000313|Proteomes:UP000295361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16998 {ECO:0000313|EMBL:TDP61498.1,
RC ECO:0000313|Proteomes:UP000295361};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDP61498.1}.
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DR EMBL; SNXS01000012; TDP61498.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R6QGN1; -.
DR InParanoid; A0A4R6QGN1; -.
DR OrthoDB; 224978at2; -.
DR Proteomes; UP000295361; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000295361};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 108..200
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
FT DOMAIN 291..358
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 366..418
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 463..699
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 716 AA; 77989 MW; 9F2702A86DF98911 CRC64;
MGALWFRGPW LAGGLALALG AGVSVQVARL DLEHQAQAQR AQVFGQLVAL QAQLVGVLKS
TFSATSGLVY LTSHQERLPA DQFNGIARRT LARLPQIRNI AVAPDDQVQL VYPLSGNEAV
LGFRYQTRPE QWATVLRARQ QRRPVLAGPV KLVQGGEALI VREPVFLDAL TPDAGPRYWG
VISIVVSVAP LLKAGGLVES HPLALHLVGS DARGDSGAPI WGNARVAQQR PVRVPVEVPG
GEWTLMATPQ GGWQTPPFWM SSYFQIGLLN SLLLAAFVVA LLSRQLRLRE SQQRFTEMAA
SIDQVFYVAA PDLSRFDYVS PAYEQMFGLP AETLLHNPRA WWDAVHPDDV DRLRSRLRGG
SWLGKVQTLW RARRADGELR NLCTSAFAVK GPDGRVQRIV GVVEDVTERL RAEQALLDLN
NTLDQRVRER TAELSDTLQH LRQTQHELVR SEKLAALGAM VAGVAHQLNT PLGSSLTLAT
ALQHQLDEFE AGTREGVRRS TLTGFVGWTR EALVSLVRNL LHATRLVEGF KQAAADQAGS
PRRSFLLDEL VQEVLVTLQP LLQGQTVAVA VQQDLAPNLR LESYPGALSQ VLAHLIENAL
LHGLHGLQGC EAPQLRIVAR RLDDCLISLS IIDNGHGIAA EHLPRIFDPF FTTRLGQGGS
GLGLHEVHKL VTGVLGGRVE VESAAGQGCC FKLTLPFEAP PLAPTEVQEV STEAAA
//
