ID A0A4R7MX09_9ACTN Unreviewed; 771 AA.
AC A0A4R7MX09;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Anaerobic selenocysteine-containing dehydrogenase {ECO:0000313|EMBL:TDU06657.1};
GN ORFNames=EDD99_5221 {ECO:0000313|EMBL:TDU06657.1};
OS Streptomyces sp. 846.5.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2485156 {ECO:0000313|EMBL:TDU06657.1, ECO:0000313|Proteomes:UP000295370};
RN [1] {ECO:0000313|EMBL:TDU06657.1, ECO:0000313|Proteomes:UP000295370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=846.5 {ECO:0000313|EMBL:TDU06657.1,
RC ECO:0000313|Proteomes:UP000295370};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDU06657.1}.
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DR EMBL; SOBN01000001; TDU06657.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R7MX09; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000295370; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000295370}.
FT DOMAIN 2..63
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 333..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 771 AA; 80411 MW; 0BD2A35A65DFF414 CRC64;
MTATTHRTCP LCEATCGLTV TIGPGPEGAG EAIGVRGDAE DPFSRGYICP KGVALGQLHS
DPARLRTPLV RRGSSWTEVS WDEAFAEGGR LLAPLLREHG ADSVGVYLGN PTVHNLGLSL
YSRTLMQALG TGYRFSASTV DQMPKQVASG LMYGTELSIA IPDIDRTDYL LVLGANPMVS
NGSLLTAPDL PGRLRALRRR GGRLVVVDPR RTRTAEIADE HLAIRPGTDA LLLAGIARTL
IEEGLADPGP RVAPHLNGLD ELGVALKPFT PEAVAAATRI PADTVRRIAR ELAAAPSAAV
YGRIGTTTTA YGTAASWLVD VVNTLTGNLD RPGGVMWPEP AAGSPTTTGE PGRGRGVRVP
GSRRTRVRGL PSVFGEFPAG ALAEEIDTPS ADADGSANGP ASGSGARLRG LITIAGNPVL
STPNSSRLGT ALASLDAMVS VDAYLNETTR HAHVVLPAAS PLARSHYDLV FASFSIRNTA
HWSPPSLPLG PGELDESEVL LRLAAAALGG TVTAQQLDDL TAADTARRIA ADPSSPAHGR
DPEELLAAVA HRSRQERLLD LMLRGGPYGD GFGAKPEGLS LDVLAAAPHG LDLGPLRPRL
PGVLRTPSGR VELAPPQLLA EAARLADHLA ELGSAPTDGL LLIGRRQLRS NNSWMHNVPL
LAGGSNRCTL QLHPADAERL GIDTGQQVQV RSRVGELHAE AEVTDGVMPG VVSLPHGWGH
DDPATRLPLA AREPGVNSNV LTDEIPLDLL SGTAVLNGIP VEVRGVVAAA P
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