ID A0A4R8RFU1_9MYCO Unreviewed; 631 AA.
AC A0A4R8RFU1;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Metallo-beta-lactamase superfamily protein {ECO:0000313|EMBL:TDZ52087.1};
GN ORFNames=CCUG63697_00558 {ECO:0000313|EMBL:TDZ52087.1};
OS Mycobacteroides franklinii.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacteroides.
OX NCBI_TaxID=948102 {ECO:0000313|EMBL:TDZ52087.1, ECO:0000313|Proteomes:UP000295165};
RN [1] {ECO:0000313|EMBL:TDZ52087.1, ECO:0000313|Proteomes:UP000295165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 63697 {ECO:0000313|EMBL:TDZ52087.1,
RC ECO:0000313|Proteomes:UP000295165};
RX PubMed=30872669; DOI=.1038/s41598-019-40922-x;
RA Behra P.R., Das S., Pettersson B.M., Shirreff L., DuCote T.,
RA Jacobsson K.G., Ennis D.G., Kirsebom L.A.;
RT "Extended insight into the Mycobacterium chelonae-abscessus complex through
RT whole genome sequencing of Mycobacterium salmoniphilum outbreak and
RT Mycobacterium salmoniphilum-like strains.";
RL Sci. Rep. 9:4603-4603(2019).
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. Type III
CC sulfatase family. {ECO:0000256|ARBA:ARBA00033751}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDZ52087.1}.
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DR EMBL; PECC01000026; TDZ52087.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4R8RFU1; -.
DR Proteomes; UP000295165; Unassembled WGS sequence.
DR GO; GO:0018741; F:linear primary-alkylsulfatase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0018909; P:dodecyl sulfate metabolic process; IEA:InterPro.
DR CDD; cd07710; arylsulfatase_Sdsa1-like_MBL-fold; 1.
DR Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR InterPro; IPR029229; Alkyl_sulf_C.
DR InterPro; IPR029228; Alkyl_sulf_dimr.
DR InterPro; IPR044097; Bds1/SdsA1_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR PANTHER; PTHR43223:SF1; ALKYL_ARYL-SULFATASE BDS1; 1.
DR Pfam; PF14864; Alkyl_sulf_C; 1.
DR Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000295165};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 102..324
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 631 AA; 68894 MW; F9450A3BEE8FC96B CRC64;
MPEQTQPTSR IIDQNAAAAQ ELPFASTVDQ ADADRGFIAA LEPGVVTDAA GKTVWDNDSY
SFLGDSCPAS VHPSLWRQCG LNIRQGLYLV TEGIYQVRGL DISNMTIVEG ENGVIVIDPL
VSAETAAAAL ALYRSHRGDR PVTGLIYTHS HADHFGGALG VVSTEDVAAG RCPVLAPAGF
LEHAVAENVY AGTAMTRRAV YMYGAVLPRG PLGQVGSGLG QTNSIGTVTL IPPTLDITHT
GQEETIDGVR MIFQLTPGTE APAEMNFHFP QHRALCMAEN ATHTLHNLLT LRGALVRDPH
VWARYITEAI NLYAHDADVV FASHHWPTWD TARLVEYLSL QRDLYAYLHD QTLRQLNQGF
VGSEIAETLQ LPPAIAGAWH ARGYYGSISH NVKAIYQRYM GWFDGNPAHL WEHPPVANAQ
RHVEFMGGSE EVLRKAHIAF EEGDYRWVAQ VVNYVIFADP ANEAAKMLQA SCFEQLGYGA
ENATWRNFYL MGAYELRHGN VGTPMAVGSP TMMAALTVDQ VFDALSLRIN GPKAWNERFV
SDWTFTDEDR VHRVELRNGV LVHYDRPAGI SPPDVTFTLT RPTLIDVLLD GKDPAQLVAS
GEIAVEGDLT GLARLVAVLD APDPGFAIVT P
//
