ID   A0A4R8RLF2_COLTR        Unreviewed;       393 AA.
AC   A0A4R8RLF2;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Arsenical-resistance protein Acr3 {ECO:0000313|EMBL:TDZ53497.1};
GN   Name=acr3 {ECO:0000313|EMBL:TDZ53497.1};
GN   ORFNames=CTRI78_v006930 {ECO:0000313|EMBL:TDZ53497.1};
OS   Colletotrichum trifolii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum orbiculare species complex.
OX   NCBI_TaxID=5466 {ECO:0000313|EMBL:TDZ53497.1, ECO:0000313|Proteomes:UP000295703};
RN   [1] {ECO:0000313|EMBL:TDZ53497.1, ECO:0000313|Proteomes:UP000295703}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=543-2 {ECO:0000313|EMBL:TDZ53497.1,
RC   ECO:0000313|Proteomes:UP000295703};
RA   Gan P., Shirasu K.;
RT   "Genome sequence and assembly of Colletotrichum trifolii.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TDZ53497.1}.
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DR   EMBL; RYZW01000069; TDZ53497.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4R8RLF2; -.
DR   STRING; 5466.A0A4R8RLF2; -.
DR   Proteomes; UP000295703; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005508};
KW   Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000295703};
KW   Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT   TRANSMEM        60..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        131..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        225..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        268..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   393 AA;  42609 MW;  4246AC5970B392F7 CRC64;
     MDMYRSPSDP SPAPARNQGG DVAEKADDGV NRDVEQQPCL DADSDKGTSV FKSLGLLDRF
     LAVWIFLAML IGILLGNFVS SAGPALQQGK FVGVSVPIAV GLLVMMYPIL CKVQYEKLHD
     VFRTREIWIQ LGFSVVINWI IAPLFMLALS WAFLPDKEGL RNGLILVGIA RCIAMVLIWT
     SLARGDGDYC AILVAVNSFL QIVFFAPVAL LFIRVIGRDD SISSISYSTV ASAVGVFLGI
     PLGAAIITRF SLVYSVGATT YNNRIIPFLA PWSLIGLLYT IIVLFASQGS QVVHQIVSVL
     RVAAPLVVYF SVIFSATLLV TRRLGFRYGL ACTQAFTAAS NNFELAIAIA VAAYGPESDE
     ALATTVGPLI EVPVLLGLVY FVQWFSRGHG WED
//