ID A0A4S2UUF1_9ACTN Unreviewed; 842 AA.
AC A0A4S2UUF1;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit {ECO:0000313|EMBL:THA76299.1};
GN ORFNames=E6R60_11705 {ECO:0000313|EMBL:THA76299.1};
OS Streptomyces sp. A0642.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2563100 {ECO:0000313|EMBL:THA76299.1, ECO:0000313|Proteomes:UP000310616};
RN [1] {ECO:0000313|EMBL:THA76299.1, ECO:0000313|Proteomes:UP000310616}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A0642 {ECO:0000313|EMBL:THA76299.1,
RC ECO:0000313|Proteomes:UP000310616};
RA Park C., Northup D., Sevigny J., Andam C.;
RT "Genome Sequencing and Assembly of Various Streptomyces sp. Isolated from
RT Bat Fecal Material.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THA76299.1}.
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DR EMBL; SSBL01000005; THA76299.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S2UUF1; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000310616; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:THA76299.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:THA76299.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:THA76299.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000310616};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 2..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 422..457
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 815..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 93137 MW; EABAE3D6783148E4 CRC64;
MFERFTDRAR RVVVLAQEEA RMLNHNYIGT EHILLGLIHE GEGVAAKALE SLGISLEAVR
QQVEEIIGQG QQAPSGHIPF TPRAKKVLEL SLREALQLGH NYIGTEHILL GLIREGEGVA
AQVLVKLGAD LNRVRQQVIQ LLSGYSGGKE AATAGGPAEG TPSTSLVLDQ FGRNLTQAAR
ESKLDPVIGR EKEIERVMQV LSRRTKNNPV LIGEPGVGKT AVVEGLAQAI VKGEVPETLK
DKHLYTLDLG ALVAGSRYRG DFEERLKKVL KEIRTRGDII LFIDELHTLV GAGAAEGAID
AASILKPMLA RGELQTIGAT TLDEYRKHLE KDAALERRFQ PIQVAEPSLP HTIEILKGLR
DRYEAHHRVS ITDEALVQAA TLADRYISDR FLPDKAIDLI DEAGSRMRIR RMTAPPDLRE
FDEKIAGVRR DKESAIDSQD FEKAASLRDK EKQLLAAKAK REKEWKAGDM DVVAEVDGEL
IAEVLATATG IPVFKLTEEE SSRLLRMEDE LHKRVIGQKD AIKALSQAIR RTRAGLKDPK
RPGGSFIFAG PSGVGKTELS KTLAEFLFGD EDALIALDMS EFSEKHTVSR LFGSPPGYVG
YEEGGQLTEK VRRKPFSVVL FDEVEKAHPD IFNSLLQILE DGRLTDSQGR VVDFKNTVII
MTTNLGTRDI SKGFNLGFAA QGDVKTNYDR MKTKVNEELK QHFRPEFLNR VDDTVVFHQL
TEEDIIQIVD LMLAKVDERL RDRDMGIELS PAAKSLLAKK GYDPVMGARP LRRTIQREIE
DILSEKILFG ELRPGHIVVV GTEGEGEEQK FTFRGEEKSA LPDVPPIEQA AGGAGPNMTK
EA
//
