ID A0A4S3MAA9_9RHOB Unreviewed; 444 AA.
AC A0A4S3MAA9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Insulinase family protein {ECO:0000313|EMBL:THD73998.1};
GN ORFNames=E7681_10350 {ECO:0000313|EMBL:THD73998.1};
OS Thalassobius vesicularis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Thalassovita.
OX NCBI_TaxID=1294297 {ECO:0000313|EMBL:THD73998.1, ECO:0000313|Proteomes:UP000306113};
RN [1] {ECO:0000313|EMBL:THD73998.1, ECO:0000313|Proteomes:UP000306113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-AMW-E {ECO:0000313|EMBL:THD73998.1,
RC ECO:0000313|Proteomes:UP000306113};
RA Hameed A.;
RT "Draft genome sequence of Youngimonas vesicularis.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THD73998.1}.
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DR EMBL; SSMD01000004; THD73998.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S3MAA9; -.
DR OrthoDB; 9811314at2; -.
DR Proteomes; UP000306113; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000306113};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..444
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5020506878"
FT DOMAIN 35..180
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 191..372
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 444 AA; 48758 MW; B10BA95AAF82F40A CRC64;
MIRAAVALLA TLVLSSPLLA AGTVSDFQLD NGMKVVVIED HRAPVVVHMV WYRAGSADEP
PGQSGVAHFL EHLLFKGTDT LAPGEFSATV ALNGGTDNAF TSYDYTAYYQ RVAADRLPLM
MKMEADRMKN LRLSEGDIVT ERNVILEERN MRVENNASAL FREQLAAAQY LNHRYGVPVI
GWRHEMAELG LDDALSFYGT YYSPNDAILV VAGDVQPDAV LDLAKQYYGV IPANPDLPAE
RYRSAEPPQT AERRLLFRDA RVAQPYVVRS YLAPERDSGA QTDAAALAIL AEVLGGSTTS
IMAEKLQFDS KTALYTAAYY GGTSLDRTTF ELVVVPAPGV TMQQAEDAMD DVLSGLLENG
IDEERLARVK MQVRASEIYA LDDTEGLANR YGRALTQGLT IQDVQEWPNV LQAVSVADVL
DVARRVLDRR QSVTGWLMSE EVGQ
//
