ID A0A4S4AWH3_9RHOO Unreviewed; 826 AA.
AC A0A4S4AWH3;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Heavy metal translocating P-type ATPase {ECO:0000313|EMBL:THF64394.1};
GN ORFNames=E6O51_03545 {ECO:0000313|EMBL:THF64394.1};
OS Pseudothauera rhizosphaerae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Pseudothauera.
OX NCBI_TaxID=2565932 {ECO:0000313|EMBL:THF64394.1, ECO:0000313|Proteomes:UP000307956};
RN [1] {ECO:0000313|EMBL:THF64394.1, ECO:0000313|Proteomes:UP000307956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-YHH848 {ECO:0000313|EMBL:THF64394.1,
RC ECO:0000313|Proteomes:UP000307956};
RA Lin S.-Y., Hameed A., Hsu Y.-H., Young C.-C.;
RT "Azoarcus rhizosphaerae sp. nov. isolated from rhizosphere of Ficus
RT religiosa.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THF64394.1}.
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DR EMBL; SSOD01000002; THF64394.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S4AWH3; -.
DR OrthoDB; 8521954at2; -.
DR Proteomes; UP000307956; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:UniProt.
DR CDD; cd00371; HMA; 1.
DR CDD; cd02079; P-type_ATPase_HM; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR021993; ATPase-cat-bd.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF5; CATION-TRANSPORTING P-TYPE ATPASE-RELATED; 1.
DR Pfam; PF12156; ATPase-cat_bd; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01229; COF_2; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Cell membrane {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000307956};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 190..209
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 229..247
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 259..281
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 287..305
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 440..462
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 468..491
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 777..793
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 799..817
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 106..172
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 826 AA; 88855 MW; 2EB7EE240112D880 CRC64;
MNTAVSETAS PAAVEDADCY HCGLPIPPET RHYVQIDGRP RRMCCVGCEA VAQSIVDNKL
TDYYRHRDAM PESRREAMPQ ELQELGLFDH PDFQKTFVRP VGEHEREASL ILEGITCAAC
VWLNEQHVAR QPGVRGIDIN YATRRARVRW DEREIKLSDI LAAVQAIGYR AYPYDAERSE
QVAHRERRSM LWRVFVAGFG MMQVMMYAIP VYMAGDGDMG ADIELLMRWA SLVLTLPVVF
YSAAPFFQRA LRDVRLRRLG MDVPVALGVG SAFAASVWAT LTGGPEVYFD SVTMFVFFLL
CGRYLEMLAR QKAVRGVEEL GKVLPVFAER LAADGSTEKV PVSQLEPGDR VRVRPGEVIP
ADGVVAEGES EANEALLTGE SRPVVKRPGA EVTGGSINVA SPLLVEVLKV GDSTRLAAIR
QLMDRATAEK PRIATQADRV ARVFIVTLLA LAAATWMAWQ FVDPDRALWV FVSVLVVACP
CALSLATPTA LTVATDVLAR MGVLITRGHA IEALAGANLY VFDKTGTLTY GRMQVDAVRV
FDGGDEARAR ALAGALEQAS EHAVAAGVRL AADGLPLPAV EGLRAVTGQG VEGRIEGRPL
RIGRPSFVAE LGASPVPEAV ATLEEGGATV VALGSADGWI ALFRLADVVR DDAPELFRRF
AGERVPTAIL SGDAPAAVNA VARRIGAGEA HAGMTPQDKQ AWVEARQREP GAMVAMVGDG
VNDAPVLAQA HVSVAMGGGT DLARNQADVV LLSESLAGLS GAIGLARRTL AVVRQNLWWS
FIYNFTSVPL AMLGLITPWM AGIGMAASSL LVVLNALRLQ ARPSSI
//
