ID A0A4S4DAR0_CAMSI Unreviewed; 445 AA.
AC A0A4S4DAR0;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 22-FEB-2023, entry version 9.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=MLO {ECO:0000256|RuleBase:RU280816};
GN ORFNames=TEA_020961 {ECO:0000313|EMBL:THF99153.1};
OS Camellia sinensis var. sinensis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Theaceae; Camellia.
OX NCBI_TaxID=542762 {ECO:0000313|EMBL:THF99153.1, ECO:0000313|Proteomes:UP000306102};
RN [1] {ECO:0000313|EMBL:THF99153.1, ECO:0000313|Proteomes:UP000306102}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Shuchazao {ECO:0000313|Proteomes:UP000306102};
RC TISSUE=Leaf {ECO:0000313|EMBL:THF99153.1};
RX PubMed=29678829; DOI=.1073/pnas.1719622115;
RA Wei C., Yang H., Wang S., Zhao J., Liu C., Gao L., Xia E., Lu Y., Tai Y.,
RA She G., Sun J., Cao H., Tong W., Gao Q., Li Y., Deng W., Jiang X., Wang W.,
RA Chen Q., Zhang S., Li H., Wu J., Wang P., Li P., Shi C., Zheng F., Jian J.,
RA Huang B., Shan D., Shi M., Fang C., Yue Y., Li F., Li D., Wei S., Han B.,
RA Jiang C., Yin Y., Xia T., Zhang Z., Bennetzen J.L., Zhao S., Wan X.;
RT "Draft genome sequence of Camellia sinensis var. sinensis provides insights
RT into the evolution of the tea genome and tea quality.";
RL Proc. Natl. Acad. Sci. U.S.A. 115:E4151-E4158(2018).
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THF99153.1}.
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DR EMBL; SDRB02012023; THF99153.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4S4DAR0; -.
DR Proteomes; UP000306102; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942:SF72; MLO-LIKE PROTEIN; 1.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR Pfam; PF03094; Mlo; 3.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000306102};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 445 AA; 50461 MW; 2E9856B4150BC4B9 CRC64;
MAKLVEEFLS LEATPTWAVA TVCFGLISIS LVIEYALLLL AKHFNKKQRK SLTQVLDKIK
SGDHNSAMIF TNGQKPIAKI CIPTSVGESF LPCKTMTSDG VEESKCEEQG KLSLMSRTGM
QQLQMLIFVL AFFHVFSSFL TFSLGLAKMK RWESWEAETK TMEYQFSNDP QRFQLINETS
FGRQHLKFWS EHRYLRLPVC FLHQFYKSVS KADYLTLRYG FITAHFANES NFDFQEYLRR
ALEKDFGVLV GISFWIWIFS VTFIFLNAHE LLSIGILYMG LGKHPQVHYL YLSHIAIETE
DIVIKLGMGL LVHILCGYVT LPLYALVAQM GTSITKAACT EGVVDGLKQW RAKAKKNIVL
RNNTNLARPS LDASMASLNN ISPSFTNLDA SFFVELDNPF TTDGGFVADK VDSEAEIEED
NLVGQRMEQY QKLGSFEGFD ICKTS
//
