ID   A0A4S4LU56_9APHY        Unreviewed;       324 AA.
AC   A0A4S4LU56;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=Dihydrodipicolinate synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EUX98_g9381 {ECO:0000313|EMBL:THH15942.1};
OS   Antrodiella citrinella.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Steccherinaceae; Antrodiella.
OX   NCBI_TaxID=2447956 {ECO:0000313|EMBL:THH15942.1, ECO:0000313|Proteomes:UP000308730};
RN   [1] {ECO:0000313|EMBL:THH15942.1, ECO:0000313|Proteomes:UP000308730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 108506 {ECO:0000313|EMBL:THH15942.1,
RC   ECO:0000313|Proteomes:UP000308730};
RA   Buettner E., Kellner H.;
RT   "Genome sequencing of the rare red list fungi Antrodiella citrinella
RT   (Flaviporus citrinellus).";
RL   Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:THH15942.1}.
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DR   EMBL; SGPM01000775; THH15942.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4S4LU56; -.
DR   Proteomes; UP000308730; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 2.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000308730}.
FT   ACT_SITE        136
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        166
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   BINDING         222
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   324 AA;  33931 MW;  782399D6D662D5EC CRC64;
     MATNAVNGHA VSSARALIPG IYGPIPTFFL PGSEDLDLES FATHIVKLAK AHVYPVIAGR
     RRALDDAGLT EVPIVAGTGT GSTRETVELS KEAAEAGADI AIVIASGYFA GALGPKALKA
     FFVEVAEKSP IPVIVYNFPG ASGGLDLDSD LITSIAEECP NTAGVKLTCG NVGKLTRICD
     TVSSASFASA YPRKNPKAPF LVFGGFIDFL LPSTYANGHG AITGLSNVAP YAIAKLYELS
     VATRIDSSLL PEAQRLQGII ARADFTIAKT SIAGTKALVE KLYGYGGVPR RPLLPLEADQ
     LDALWAHPHV QDLVKLEREL SGKS
//