ID A0A4T0VC51_9ACTN Unreviewed; 765 AA.
AC A0A4T0VC51;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=FdhF/YdeP family oxidoreductase {ECO:0000313|EMBL:TIC89301.1};
GN ORFNames=E8D34_02110 {ECO:0000313|EMBL:TIC89301.1};
OS Nocardioides sp. GY 10113.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=2569761 {ECO:0000313|EMBL:TIC89301.1, ECO:0000313|Proteomes:UP000304990};
RN [1] {ECO:0000313|EMBL:TIC89301.1, ECO:0000313|Proteomes:UP000304990}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GY 10113 {ECO:0000313|EMBL:TIC89301.1,
RC ECO:0000313|Proteomes:UP000304990};
RA Shi S.;
RT "Nocardioides sp.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TIC89301.1}.
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DR EMBL; STGK01000001; TIC89301.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4T0VC51; -.
DR OrthoDB; 9759518at2; -.
DR Proteomes; UP000304990; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000304990}.
FT DOMAIN 122..492
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 647..734
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 765 AA; 82306 MW; 411AE80C3E5C9F38 CRC64;
MATRAPNGEP DESRLEVSAA PEHSAGPRAV AAAMRHAVGQ MGVRRSAATL RRVNQADGFD
CQGCAWPDAE AGHRHVAEFC ENGAKAVAEE ATLRRVDAGF FAEHSVADLA GHGDYWLGQQ
GRLTEPMVLR PGATHYAPIG WDEAFALVAD HLRGLDHPDQ AVFYTSGRTS NEAAFVYQLL
VRAFGTNNLP DCSNMCHEST SVALTETIGI GKGSVTLTDV ETADLIVVAG QNPGTNHPRM
LASLEVAKDN GARIISVNPL REAGLGRFKN PQRPRGVVGH GTRLADLHLP IRLGGDLALF
QAWGALLLKW GAIDEEFLAE HTVGFTAYAE GLADLDWDKV EEATGLTRDQ IEEGAAMIRD
SAATVWCWAM GLTQHRHGVA TIKEVVNLAL LRGDIGRPGA GLCPVRGHSN VQGDRTMGIW
ERPPVWFLDA LEVEFGIPVP REHGLDVVEA IRALSTGAAR VFVGLGGNFA SAAPDTPVTE
AALRRADLTV QISTKLNRSH AVPGTTALIL PVLGRSERDL TGGSPQRVTV EDSMSMVHAS
RGPLAPASPE LRSEVDVVCS IALALFAEDH PGSGVPWERL RTDYGEIRHR ISRVIPGFDD
YERRIDQPGG FVLPHPPRDA RVFPTAAGRA VLTVSPLDVL DLPEGHLLLQ TLRSHDQYNT
TIYGLDDRYR GIRNGRRVVF VHPDDVADLG LAGGDLVDLV AVWGDGVERR ADRFRVVPYD
QPRGCAAAYY PETNPLVPLG SVAVGSNTPT SKSVVVRLEP HGGGR
//
