ID   A0A4T0WYY9_9ASCO        Unreviewed;      1317 AA.
AC   A0A4T0WYY9;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CANINC_003292 {ECO:0000313|EMBL:TID22517.1};
OS   [Candida] inconspicua.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Pichiaceae; Pichia.
OX   NCBI_TaxID=52247 {ECO:0000313|EMBL:TID22517.1, ECO:0000313|Proteomes:UP000307173};
RN   [1] {ECO:0000313|EMBL:TID22517.1, ECO:0000313|Proteomes:UP000307173}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 180 {ECO:0000313|EMBL:TID22517.1,
RC   ECO:0000313|Proteomes:UP000307173};
RX   PubMed=31105748; DOI=10.3389/fgene.2019.00383;
RA   Mixao V., Hansen A.P., Saus E., Boekhout T., Lass-Florl C., Gabaldon T.;
RT   "Whole-Genome Sequencing of the Opportunistic Yeast Pathogen Candida
RT   inconspicua Uncovers Its Hybrid Origin.";
RL   Front. Genet. 10:383-383(2019).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TID22517.1}.
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DR   EMBL; SELW01000541; TID22517.1; -; Genomic_DNA.
DR   STRING; 52247.A0A4T0WYY9; -.
DR   Proteomes; UP000307173; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000307173}.
FT   DOMAIN          10..221
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          241..536
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          549..717
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          740..1279
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1317 AA;  144519 MW;  6D2531D34620B316 CRC64;
     MTIPTGGISI AIDRGGTFTD VIFKYNGVEE TFKLLSVDPS NYDDANIEGI RRVLEKVTGK
     VIKRGEKLDT KCISSIRLGT TVATNALLER KGAKCALVTT KGFKDLLHIG DQSRPDLFAL
     NIVKPGVLFE KVVEADERVT MPAFLVDPTG YDAKDLVDNK EYVLGETNEV FQILKPLDTQ
     KLEQDLRKIK DEGVDSIAIV FIHGFNYQKH EKQAGEIAEK IGFKHISLSH EILPVIKAVP
     RGQSTVVDAY LTPIVKDYIK SFLSGFKEDF EQHTRIEFMQ SDGGLCSWKN FTGLKSLLSG
     PAGGVVGEAK TCYDKENKIP LIGFDMGGTS TDVSRYAGEY EFSFESTTAG IKIAAPQLDI
     NTVAAGGGSI LTYRNGVFAV GPESASAHPG PACYRKGGPL TITDANLFTG RILPEFFPKI
     FGPNEDQELD FEITKKKFEE LTEQINKENP GITKTPQEVA LGFLEVANFQ MSKPIRDLTE
     AKGHNVATHS LASFGGAGGQ HAGAIAKILK IKKVIIHKHS SILSAYGISL ADVVKEIQEP
     CAETYSESSK EKLLSKCEEL RKQCCEELKE QGVSESTIDY DIYFNMGYKG SDTKIMISQP
     EDGDFLKKFY DIHEREFAFN DKEKDVLVSD IRVRGTGNVI GGDGERSPYK DFETVEKKLV
     KEGLEEKTTP IYFDEGYLQS KFYFLNKLEI GTIIPGPALI LDDTQTILVN PGSTAVILPR
     HIMMDVDIEN NVNISTDYVD PIQLAIFANR FMSIADDMSR TLQKISVSAN IKERMDYSCA
     LFDNEGNLTA NAPNVPVHLG SMSAAIRYQL ERWGDDLHDG DILCTNSPSV GGTHLPDITI
     ISPVFYEGKI QFVVAARAHH SEIGGSAPGS SSSYAREIFE EGVNIESWKV VSNGKFDYEG
     LKKHFVDEPR THGVSGTRNL DDNLSDLKAQ IASNQRGINL LKELFDEYGS ETVLFYMKNI
     KKTAEAAVRS FLKKYAAEHR DKLPLRAVDY MDDGSKIQVK IDINEEDGSA VFDFTGTSLE
     SYSNLNAPRS ITFSTVIYTL RCLVNTDIPL NQGCLDPCTL IIPENSLINP SRFAAVCAGN
     GMTSQRITDC LFKAFGFTSA TGGCMNGLNF GSGGLDANGN MVKGFGYTET IGQGNCAGIV
     EKNGVRTGFN GFSGTQTNMT NTKITDPEIF EQRYPVVLIQ YCIRHGSGGR GKWNGGNGLI
     REIRFTSPVH VSLVTQRRVF APWGIYGGED GKKGVNKLGR NRGNGIIQWI QLPSLAEIAM
     RKGDILWVAT PGGGGFGKPT DTDEFWNITS TTKKQFEHVP LSSGTFGTLV EAANTSQ
//