ID A0A4U0TU71_9PEZI Unreviewed; 891 AA.
AC A0A4U0TU71;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B0A50_05861 {ECO:0000313|EMBL:TKA25764.1};
OS Salinomyces thailandica.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Teratosphaeriaceae; Salinomyces.
OX NCBI_TaxID=706561 {ECO:0000313|EMBL:TKA25764.1, ECO:0000313|Proteomes:UP000308549};
RN [1] {ECO:0000313|EMBL:TKA25764.1, ECO:0000313|Proteomes:UP000308549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCFEE 6315 {ECO:0000313|EMBL:TKA25764.1,
RC ECO:0000313|Proteomes:UP000308549};
RA Coleine C., Masonjones S., Stajich J.E.;
RT "Genomes of endolithic fungi from Antarctica.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TKA25764.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NAJL01000033; TKA25764.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4U0TU71; -.
DR Proteomes; UP000308549; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17356; MFS_HXT; 1.
DR CDD; cd06466; p23_CS_SGT1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 4.10.1130.20; -; 2.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR007051; CHORD_dom.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR NCBIfam; TIGR00879; SP; 1.
DR PANTHER; PTHR48022:SF14; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR48022; PLASTIDIC GLUCOSE TRANSPORTER 4; 1.
DR Pfam; PF04968; CHORD; 2.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51401; CHORD; 2.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000308549};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 57..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..522
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 576..632
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 707..768
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT DOMAIN 783..873
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 628..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..660
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..699
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 99073 MW; 1FA7D0E93603F8CC CRC64;
MAEKLDELHT SDYIEDVGTE VARSGSAMAA DHSEKPVWEQ RQLYGPPGIR GIFKSRYVFA
AAAFATLGGT LFGYDQGVVS ITLVMPQFLD QFPEIGPDSV DSSFKKGLLT AMIELGAFLG
AMNQGWIADK ISRKWSILLA ACIFLIGSAI QTGSVNYGML TGARFVGGIG VGMFAMVTPL
YISEIAPPEI RGTLLVLQEL SITTGIVVAY YITYGTRYIG GDWAWRLPFL IQMMPAILLG
LGVPFLPYTP RWLCQTGRDD QALKTLAKLR QQPESDSRVQ QEWYEIRSEV AYRREIQQER
YPKLQDGTVR SRMLLQANNW ADCWRRQGWK RTQVGVGLMF FQQFVGINAL IYYSPTLFET
MGLGYEMQLT MSGVLNVCQV VACVCSLWGM DKFGRRKLLL GGGVCMFASH FIIAVLVGLY
SGKWEDHAAA AWTSVAFLLF FMFTFGATWG PIPWAMPAEV FPSSIRAKGC AQATMSNWGN
NFIIGLITPP MLSSIGFGTY VFFAAFCLLA LIWVWFFVPE TMGRTLEQMD FVFKDNQSQD
ELARRARIEA AMTQRIQREA NEKLRQSTSS NMAQKCVHKG CGKLFTDPED PCSYHPGPPV
FHEGQKGWKC CKPRVLTFDE FMTIPPCTTG KHSTVDDTPA PEPQSSKEDV DAKIEASRVK
KEQGTAQPAV SRQPIAAAQP PQPSSSPAPP EPEDDDPSLP IPANVPCKRR ACTATYTPSA
NRDNEQCLHH PGHPIFHEGS KGYTCCKRRV LEFDDFLNMP GCTTTSYHLF VGAKKDPKAE
ETLKDIRNDF YQTATTVIAS LYLKKIDKER SKVAFPAADT VELDLHTADQ TRYTTRMVTF
GPIDPEKSSF KIMGTKLELT LVKADGVGWP VLRKDDPHTG EIIQAGRAGR V
//
