ID A0A4U0X0Q9_9PEZI Unreviewed; 1220 AA.
AC A0A4U0X0Q9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B0A49_08122 {ECO:0000313|EMBL:TKA67795.1};
OS Cryomyces minteri.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Cryomyces.
OX NCBI_TaxID=331657 {ECO:0000313|EMBL:TKA67795.1, ECO:0000313|Proteomes:UP000308768};
RN [1] {ECO:0000313|EMBL:TKA67795.1, ECO:0000313|Proteomes:UP000308768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCFEE 5187 {ECO:0000313|EMBL:TKA67795.1,
RC ECO:0000313|Proteomes:UP000308768};
RA Coleine C., Masonjones S., Stajich J.E.;
RT "Genomes of endolithic fungi from Antarctica.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TKA67795.1}.
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DR EMBL; NAJN01000877; TKA67795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4U0X0Q9; -.
DR STRING; 331657.A0A4U0X0Q9; -.
DR Proteomes; UP000308768; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF72; GH08340P; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 2.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000308768};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..132
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 202..463
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 474..559
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 1153..1216
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..611
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1220 AA; 133802 MW; 5A12AC99BAB04AF6 CRC64;
MHGHADDKTQ HPGKPKPGSF PRPVGGSAKL GTFAGVFVPT SLNVLSILMF LRFGFILGQS
GVVGMMVMLI ACYAINLVTT MSISAIASNG TVRGGGAYYL ISRSLGPEFG GSIGIVFYLG
FVFNTGMNAV GLIDCLKQNF GVETGNWANW LPEGFWLQYL WATVVLLACL SWETFKNNLM
PHFTRGADGS QVHGKETYQD LFGILFPATG GIFAGASMSG DLKHPSKAIP KGTLYGLLLT
FFAYAVVILA MAASISRTSF YHNVNVIQDV NVSGVLILLG ECATSLFSSL MGVIGSAKLL
QALARDHLLP GLSVFGQGTK GSDEPTYAII VTYIVAQLTM LSDINQIASF VTMTYLMTFL
VTNLACFLLK VSSAPNFRPS FHYFNWWTAA IGTIVSGATM FFVDGVYASA CVGVLVVIFL
IIHYTTPPKS WGDVSQSLIY HQVRKYLLRL RQEHVKFWRP QILLLVNDPR RQFKLIQFCN
SLKKGALFVL GHVIVTQDFG GAVPEARRQQ TAWTKYIDFS RVKAFVNIAI SPAVEWGARN
IVLSAGLGGM RPNIVVMGFF NLTEYRRTEP LIPIPSPQPC RSSTAASTQP SPNDLKKRRR
SKDDKLKGQL PTDLNRPEGA VGVQSYVTIL EDLLHRLQIN VAIARGFQEL EFPAHRPSKK
ERALSLLHLT QKDEEENTKK YIDLWPIQMS AEIAAEGGER RQNVLTTNFD TYTLILQLGC
ILHTVPAWKR AYKVRVAVFV EYESDVEEER GRVKTLLSNL RIEAEVLVFW LASGALKTYE
IIVNGDNEGP NSEAVPDVDD ALKDEGWWED VEKIRGRKGG LSASQELVHV QGFVDAVQNW
PSSSFQHGRR NSKLERFDEL RKMLRRSRKH HSVSGLNRFG ASLGMRTHRL HPDLLDRHAS
HGSASEDSGL DSDVFEGSES DGSNSDHGSA ASENDIDEYM TDSDEGSSSP TPDPPLRSRS
LSVGGAVQGW PRPSHHKSGF RHAAHGPRTA AASSSSFKRF DLASVRPDAT ASDSSHGGTS
APASDRRPTV TLNDDSERPS SATDLHQPSI RPPVMRQQST PKFISKPMPR TQVASEDGPG
PSIMFTDQPS PPTQQRLPHR SIYEHKRSPN SSGNTKADLN PFDSTQAQSA SASGYPAQRA
IPLSFNDLPC RAQHLILNEL IQSASADTAV VFTTLPSPFE GTCENAEDSV RYLADLEVLC
KDLPPVLLVH SNSMTVTMSL
//
