ID A0A4U1FR03_MONMO Unreviewed; 808 AA.
AC A0A4U1FR03;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 9.
DE RecName: Full=PKD domain-containing protein {ECO:0000259|PROSITE:PS50093};
DE Flags: Fragment;
GN ORFNames=EI555_004521 {ECO:0000313|EMBL:TKC52662.1};
OS Monodon monoceros (Narwhal) (Ceratodon monodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Monodontidae; Monodon.
OX NCBI_TaxID=40151 {ECO:0000313|EMBL:TKC52662.1, ECO:0000313|Proteomes:UP000308365};
RN [1] {ECO:0000313|Proteomes:UP000308365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=31054839; DOI=10.1016/j.isci.2019.03.023;
RA Westbury M.V., Petersen B., Garde E., Heide-Jorgensen M.P., Lorenzen E.D.;
RT "Narwhal Genome Reveals Long-Term Low Genetic Diversity despite Current
RT Large Abundance Size.";
RL IScience 15:592-599(2019).
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TKC52662.1}.
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DR EMBL; RWIC01000023; TKC52662.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4U1FR03; -.
DR Proteomes; UP000308365; Unassembled WGS sequence.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861:SF1; MELANOCYTE PROTEIN PMEL; 1.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000308365};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 378..418
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 47..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:TKC52662.1"
FT NON_TER 808
FT /evidence="ECO:0000313|EMBL:TKC52662.1"
SQ SEQUENCE 808 AA; 85382 MW; D4559C87E1C03901 CRC64;
PKCHKSFTNY GQEISGWLGI PKPSSNAENE SLIAHDMRNR RLEETQRLRP KPARGEAKGK
KAGCHRGVRA EDWTGGAPDQ YREGNFEDGR APLVAGKKNR MDLVLRKCLL HVAVMGALLA
VGATEGPRDW DWLGVSRQLR TKAWNRQLYP EWTESQGPHC WRGRNLAISG EGMVGMGWGE
ERSKNWVECG QVSLKVSNDG PTLRGANASF SIALHFPESQ KVLSDGQVIW ANNTIINGSQ
VWGGQPVYPQ EPDDTCIFPD GRACPSGPSP QRRSFVYVWK TWGQYWQVLG GPVSGLSIGT
GKAVLGTHIM EVTVYHRRGS QSYVSLAHSR SAFTITDQVP FSVSVSQLQA LDGTNNHFLR
KQPLTFALQL HDPSGYLAGA DLSYTWDFGD STGTLISRAL VVTHTYLESG PVTAQVVLQA
AIPFTSCGSS PVPGTTAGHV PTAEAPGTTA GQVPTAEVVA TTPAQVPTAE PSGTTAVQVP
TAEGTGTTAG QVPTAEVVAT TPAQMPTAEP SGTTAVQVPT AEGTGTTAEQ VLASEVVSTT
PAEMPTAEAI GTTPEVSTAE PSGTTVAQVT TTELVETTAG EVPTPEPDSP DASPFLSTEG
ITGSQSPLLD DTATLILVKR QVPLDCVLYR YGSFSLTLDI VQGIESAEIL QAVPSSEGDA
FELTVSCQGG LPKEACVDIS SPGCQPPAQR LCQPVPPSPD CQLVLHQVLK GGSGTYCLNV
SLADADSLAM VSTQLVMPGR YLDERSRSRL RAGSPVLGHL AGIDGFAARI SGIQEKTYEA
GPSSPPSPAA TRQNPVATSA LGLPHLPH
//
