ID A0A4U6TCD9_SETVI Unreviewed; 397 AA.
AC A0A4U6TCD9;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:TKV99737.1};
GN ORFNames=SEVIR_8G063200v2 {ECO:0000313|EMBL:TKV99737.1};
OS Setaria viridis (Green bristlegrass) (Setaria italica subsp. viridis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria.
OX NCBI_TaxID=4556 {ECO:0000313|EMBL:TKV99737.1, ECO:0000313|Proteomes:UP000298652};
RN [1] {ECO:0000313|EMBL:TKV99737.1, ECO:0000313|Proteomes:UP000298652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. A10 {ECO:0000313|Proteomes:UP000298652};
RA Huang P., Jenkins J., Grimwood J., Barry K., Healey A., Mamidi S.,
RA Sreedasyam A., Shu S., Feldman M., Wu J., Yu Y., Chen C., Johnson J.,
RA Rokhsar D., Baxter I., Schmutz J., Brutnell T., Kellogg E.;
RT "WGS assembly of Setaria viridis.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM016559; TKV99737.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4U6TCD9; -.
DR EnsemblPlants; TKV99737; TKV99737; SEVIR_8G063200v2.
DR Gramene; TKV99737; TKV99737; SEVIR_8G063200v2.
DR OMA; AIANCIC; -.
DR Proteomes; UP000298652; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF859; PEPT_C1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000298652};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..141
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 172..380
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 397 AA; 42747 MW; E65D92A1F6154782 CRC64;
MDSDQQYTLS SLQLPASIIL AHTHHLHTAA TAMAPYIANK KPLVTMALIL LAVLTIANCI
CCTVAARDLP GSGSVAEAAM MVRFERWVTE HGRTYKDAAE KARRFQVFMA NAIFVDSSNA
AGGKKYHLAI NGFADMTHDE FMARYTGYKA TPATGMKMPG FQYGNVTQSE PQQAEVDWRQ
KGAVTGVKNQ EDCGCCWAFS AVAAIEGIHH IKTGELVSLS EQQVLDCSTN GNHGCNGGNM
DNAFEYIISN GGITTEDAYQ YTAIQDMCQS VQPAVTIRSY QDVPRYDEDA LAAAVANQPV
SVGVDANNFQ FYDGGVMTTD SCGTDLNHAV TIVGYGTAED DSQYWLIKNS WGETWGEGGY
LRLERGVNAC GVAIQASYPV AGVNAYGVAI QASYPVA
//
