ID A0A4U8SB71_9HELI Unreviewed; 447 AA.
AC A0A4U8SB71;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=C4-dicarboxylate transporter DcuA {ECO:0000256|ARBA:ARBA00039380};
GN ORFNames=LS70_005535 {ECO:0000313|EMBL:TLD83211.1};
OS Helicobacter sp. MIT 11-5569.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1548151 {ECO:0000313|EMBL:TLD83211.1, ECO:0000313|Proteomes:UP000029923};
RN [1] {ECO:0000313|EMBL:TLD83211.1, ECO:0000313|Proteomes:UP000029923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 11-5569 {ECO:0000313|EMBL:TLD83211.1,
RC ECO:0000313|Proteomes:UP000029923};
RX PubMed=25428971;
RA Sheh A., Shen Z., Fox J.G.;
RT "Draft genome sequences of eight enterohepatic helicobacter species
RT isolated from both laboratory and wild rodents.";
RL Genome Announc. 2:e01218-e01214(2014).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
CC {ECO:0000256|ARBA:ARBA00006413}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TLD83211.1}.
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DR EMBL; JRPB02000005; TLD83211.1; -; Genomic_DNA.
DR RefSeq; WP_034287659.1; NZ_JRPB02000005.1.
DR AlphaFoldDB; A0A4U8SB71; -.
DR STRING; 1548151.LS70_02605; -.
DR OrthoDB; 9770910at2; -.
DR Proteomes; UP000029923; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015556; F:C4-dicarboxylate transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004668; Anaer_Dcu_memb_transpt.
DR NCBIfam; TIGR00770; Dcu; 1.
DR PANTHER; PTHR36106:SF2; ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUA; 1.
DR PANTHER; PTHR36106; ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUB; 1.
DR Pfam; PF03605; DcuA_DcuB; 1.
DR PIRSF; PIRSF004539; C4-dicrbxl_trns; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 447 AA; 46925 MW; 62CD657C55B99833 CRC64;
MDIMLILQII VLLGAIFVGI RLGGIAIGYA GGLGVVILGL ALGMKPGSIP WDVILIIMSV
IAAISAMQLA GGLDYLVQIA ERILRSNPKY INYLAPTVTY FLTILAGTGH TAFSMIPVIV
EVAKEQNIKP SAPLSIAVVA SQIAITASPV SAAVVYMTGV LEPLGWSYPL LLAIWIPTTF
VGCMLTALII TMFSNLDLSS DPVYQDRLAK GLVKPAVGAQ NMQLKEGAKL SVGIFVIGVL
LVVLYATAIS KIGGKPVLIE NVIVPRDAAI MSFMLAVATF ITIFCKIEVG KIAESSVFKS
GMIACVCVLG VAWLGNTFVG GYTEEIKTLA GDWVKAIPSL LAVIFFFAAM LLYSQAATAK
AITPVVVMAL GITAANPGDS YMLVASFAAV SALFVLPTYP TLLGAVQMDD TGSTRIGHYI
FNHAFLIPGV LAIVFSVALG FVATAFV
//
