ID   A0A4U8UCA1_9HELI        Unreviewed;       710 AA.
AC   A0A4U8UCA1;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=RNA pseudouridylate synthase {ECO:0000256|ARBA:ARBA00031870};
DE   AltName: Full=RNA-uridine isomerase {ECO:0000256|ARBA:ARBA00033164};
GN   ORFNames=LS79_007325 {ECO:0000313|EMBL:TLE09798.1};
OS   Helicobacter bilis.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=37372 {ECO:0000313|EMBL:TLE09798.1, ECO:0000313|Proteomes:UP000029857};
RN   [1] {ECO:0000313|EMBL:TLE09798.1, ECO:0000313|Proteomes:UP000029857}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49320 {ECO:0000313|EMBL:TLE09798.1,
RC   ECO:0000313|Proteomes:UP000029857};
RX   PubMed=25428971;
RA   Sheh A., Shen Z., Fox J.G.;
RT   "Draft genome sequences of eight enterohepatic helicobacter species
RT   isolated from both laboratory and wild rodents.";
RL   Genome Announc. 2:e01218-e01214(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TLE09798.1}.
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DR   EMBL; JRPJ02000025; TLE09798.1; -; Genomic_DNA.
DR   RefSeq; WP_034579515.1; NZ_JRPJ02000025.1.
DR   AlphaFoldDB; A0A4U8UCA1; -.
DR   Proteomes; UP000029857; Unassembled WGS sequence.
DR   GO; GO:0140098; F:catalytic activity, acting on RNA; IEA:UniProt.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   Gene3D; 3.30.2350.10; Pseudouridine synthase; 2.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR006224; PsdUridine_synth_RluA-like_CS.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR   PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR   PANTHER; PTHR21600:SF100; RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   SUPFAM; SSF55120; Pseudouridine synthase; 2.
DR   PROSITE; PS01129; PSI_RLU; 1.
PE   4: Predicted;
FT   DOMAIN          101..245
FT                   /note="Pseudouridine synthase RsuA/RluA-like"
FT                   /evidence="ECO:0000259|Pfam:PF00849"
SQ   SEQUENCE   710 AA;  82514 MW;  B07B29E2FC3F57C4 CRC64;
     MGFKTISLQV AERIKATHFL LQNGYSKKDT QKLLDKNRIK QDSKIIHKKD FLEKGHVEIL
     SFMPDDIKLT PFFACVPPNH VILQQDIPIL EIKISQNPPY FCVFNKPSKL LTHPKNLADS
     KSILDSLRYY FGKHANPCHR LDYETSGLLV CSIDKQSEIM LKNLFLQKGV KKSYMAILHG
     EVKESLLIES EIIFLKDFGN LCIKGRAKDL RVKTIKENEI KVITKDSIQQ DQSRATTILT
     PLHVFHSFNE VSSYLYKSSN PFFSHKALVP LTLQENLADI SRDFIQDFMF FTECDYDKKI
     KQDSMARKSD DFTLQYSDFF NEKKLLQCYE SFLNVWGAGF RAQNNILDSH TYHTEPLGEV
     SKKLDFKPAC HIECKQTSKG LESKKNILPN THSKISLENN KKLDFITAFH TDFQQSKKEI
     SKNLESKQNE KFTLVKLFPL SGKTHQLRIH TSSLQHKILG DTLYGLCPVV ASLFLDLQSK
     KLKANIESYL FETLTKKHSS SIQKYVYAIH YLRRDKNITQ KMLYNVMLNF NIACKTIEAK
     TACHIEQSET SNMESKQRLN SKIDLNTDSK NIQITESKYF VLPFCKFLSL SLSKILISCF
     FSQKYNKTNR ASFLSYFLYD DTESISQCLH PKPHYRSNEI DSKLSQPHSK IQTFNKDFEF
     FFFTFLLFYY ALPSHQEKIL KDIRLHYCST DRLLLHASSL SFLEECFTCE
//