ID A0A4U8UFX1_9HELI Unreviewed; 747 AA.
AC A0A4U8UFX1;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=PD-(D/E)XK nuclease family protein {ECO:0000313|EMBL:TLE16449.1};
GN ORFNames=LS72_003145 {ECO:0000313|EMBL:TLE16449.1};
OS Helicobacter apodemus.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=135569 {ECO:0000313|EMBL:TLE16449.1, ECO:0000313|Proteomes:UP000029920};
RN [1] {ECO:0000313|EMBL:TLE16449.1, ECO:0000313|Proteomes:UP000029920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT-03-7007 {ECO:0000313|EMBL:TLE16449.1,
RC ECO:0000313|Proteomes:UP000029920};
RX PubMed=25428971;
RA Sheh A., Shen Z., Fox J.G.;
RT "Draft genome sequences of eight enterohepatic helicobacter species
RT isolated from both laboratory and wild rodents.";
RL Genome Announc. 2:e01218-e01214(2014).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TLE16449.1}.
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DR EMBL; JRPC02000006; TLE16449.1; -; Genomic_DNA.
DR RefSeq; WP_034554782.1; NZ_JRPC02000006.1.
DR AlphaFoldDB; A0A4U8UFX1; -.
DR Proteomes; UP000029920; Unassembled WGS sequence.
DR Gene3D; 3.90.320.10; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR PANTHER; PTHR36531; CRISPR-ASSOCIATED EXONUCLEASE CAS4; 1.
DR PANTHER; PTHR36531:SF6; DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029920}.
FT DOMAIN 512..744
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
SQ SEQUENCE 747 AA; 88792 MW; D547216BF08E760F CRC64;
MSLQTLYLFS TSRAIKFFYQ NHQGFLPSTQ SIGEFLEFIL RVENKVKIPD FLRLIYLYEA
IRENQTKSFG EFAKNFSQFL LNSSFFLKFY DELCAECIVL EQLEKLDIYA FYDDHLKVLK
AIFKTYKQKL DSNGFFDKYF LEDFKITFDL LKNYHQIEIA LDGFLSRFEM LVFEEISFYK
PVFFKLDIQV FNQKYYENLF NLSLDFGEVM VKLESQKIEK VFFKKNSDDK AGAIHILQTP
DRITQVGASF MQIDKWLAKG ITPEEICVIL PNEDFIKYLQ LFDKARNFNF AMGKKITETS
LFKLLLESLE KFKDLESLET FLAEFKEETQ EDKKVKTRFY EVLEKFYCGL KYLHHLSPKD
QIVAFLFMLE QESLDDVGGG RISVMGILET RGIRFNYVLI PEFIEENVPA LSHKDIFLNT
TIRQKVGLPT RVDRENLQKY YYSQLFKRSK EVWILTLDNQ EDKPSRFLLD ERVFSQKQVL
EGNVLAFGQY FLRGRALNYQ EVEIIEPLEL EFSPTSLECF LTCKRKYYYR YIQGFKERKE
TFNIGSKVHK ALQEGFSEFL EKRDFQQVIQ KTYESLEISL NQQEKFLSQL AKKYLEVFFK
KEEKRLQEGW IPLALEREFS MKFCGIPFYG KIDRIDKRGE EILILDYKYK KEIQCDTLKN
YEKSKDFQLA IYALAVKEFG LGESIEAAFY SICQSQIVYE EVLVQKQEYL SKYLAEIKSK
AKAISFELTS KREVCRNCVF IYLCNRY
//
