ID A0A4U8UQF2_STECR Unreviewed; 487 AA.
AC A0A4U8UQF2;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};
GN ORFNames=L596_002751 {ECO:0000313|EMBL:TMS35322.1};
OS Steinernema carpocapsae (Entomopathogenic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Steinernematidae;
OC Steinernema.
OX NCBI_TaxID=34508 {ECO:0000313|EMBL:TMS35322.1, ECO:0000313|Proteomes:UP000298663};
RN [1] {ECO:0000313|EMBL:TMS35322.1, ECO:0000313|Proteomes:UP000298663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALL {ECO:0000313|EMBL:TMS35322.1,
RC ECO:0000313|Proteomes:UP000298663};
RX PubMed=26392177; DOI=10.1186/s13059-015-0746-6;
RA Dillman A.R., Macchietto M., Porter C.F., Rogers A., Williams B.,
RA Antoshechkin I., Lee M.M., Goodwin Z., Lu X., Lewis E.E.,
RA Goodrich-Blair H., Stock S.P., Adams B.J., Sternberg P.W., Mortazavi A.;
RT "Comparative genomics of Steinernema reveals deeply conserved gene
RT regulatory networks.";
RL Genome Biol. 16:200-200(2015).
RN [2] {ECO:0000313|EMBL:TMS35322.1, ECO:0000313|Proteomes:UP000298663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ALL {ECO:0000313|EMBL:TMS35322.1,
RC ECO:0000313|Proteomes:UP000298663};
RX PubMed=31113823;
RA Serra L., Macchietto M., Macias-Munoz A., McGill C.J., Rodriguez I.M.,
RA Rodriguez B., Murad R., Mortazavi A.;
RT "Hybrid Assembly of the Genome of the Entomopathogenic Nematode Steinernema
RT carpocapsae Identifies the X-Chromosome.";
RL G3 (Bethesda) 0-0:2687-2697(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361216}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148,
CC ECO:0000256|RuleBase:RU361216}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TMS35322.1}.
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DR EMBL; AZBU02000001; TMS35322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4U8UQF2; -.
DR STRING; 34508.A0A4U8UQF2; -.
DR Proteomes; UP000298663; Chromosome x.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; IEA:UniProt.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR11958:SF108; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR11958; SODIUM/DICARBOXYLATE SYMPORTER-RELATED; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
DR PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361216};
KW Reference proteome {ECO:0000313|Proteomes:UP000298663};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU361216};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361216};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361216};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361216}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 59..80
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 92..116
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 233..254
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 266..292
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 304..325
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 378..395
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
FT TRANSMEM 401..427
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361216"
SQ SEQUENCE 487 AA; 52352 MW; 14CA3387E8C31343 CRC64;
MTRKIGEFSL ISGRWTTEQT QLALTIVAIF GGIALGFIIR TQEPSEKTVH LIGFPGEIFM
NMLKMIILPL IMASLISGLS QLDAKQSGRM SAYAFAYYAL TTSVAVLTGI ALVLLIHPGD
ASAKIQQDRL AEQEQSVSAF DKFLDLIRNM FPDNIVQASF QQTQTDYQTT IISQADNSTK
ESLNVTEKKV DGMNVLGFIV FCIVFGIVIG QVGEKAKVLA DFFTALDLVM TRIVVIVMWY
SPVGIASLIA AKILGIANLA DTARMLGVYM LTVIAGLTIH LFLTVPLIYF AVSRKNPYKF
MKGLLQAALT ALGTASSAAT LPITFRVLEL NNKVDPRITK FVLPVGATIN MDGTALYEAV
ASVFIAQING IELSFGQVAT VSLTATLASI GAASIPSAGL VTMLIVLTAV GLPTSDISLI
ITVDWLLDRL RTCVNVLGDG FGCGCVHELC SKDLDLNRGS EIPTIIVNGE LELECKQATT
GSNKSIY
//
