ID   A0A4V0INP7_CAEEL        Unreviewed;       511 AA.
AC   A0A4V0INP7;
DT   31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT   31-JUL-2019, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Potassium channel domain-containing protein {ECO:0000313|EMBL:VTW47620.1};
GN   Name=unc-58 {ECO:0000313|EMBL:VTW47620.1,
GN   ECO:0000313|WormBase:T06H11.1g};
GN   ORFNames=CELE_T06H11.1 {ECO:0000313|EMBL:VTW47620.1}, T06H11.1
GN   {ECO:0000313|WormBase:T06H11.1g};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000313|EMBL:VTW47620.1, ECO:0000313|Proteomes:UP000001940};
RN   [1] {ECO:0000313|EMBL:VTW47620.1, ECO:0000313|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000313|EMBL:VTW47620.1,
RC   ECO:0000313|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RA   Sulson J.E., Waterston R.;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC       1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC       ECO:0000256|RuleBase:RU003857}.
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DR   EMBL; BX284606; VTW47620.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A4V0INP7; -.
DR   EnsemblMetazoa; T06H11.1g.1; T06H11.1g.1; WBGene00006792.
DR   AGR; WB:WBGene00006792; -.
DR   WormBase; T06H11.1g; CE53293; WBGene00006792; unc-58.
DR   OrthoDB; 2873458at2759; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   ExpressionAtlas; A0A4V0INP7; baseline and differential.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR003280; 2pore_dom_K_chnl.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR   PANTHER; PTHR11003:SF310; UNCOORDINATED PROTEIN 58; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   PRINTS; PR01333; 2POREKCHANEL.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:VTW47620.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003857};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003857};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        317..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        373..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          206..263
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
SQ   SEQUENCE   511 AA;  58166 MW;  DBC2B524BD11C931 CRC64;
     MIFSQAFRNE QFSPAVALFS AAGLIKTTAG IKEEEENEQQ NNRKKDHVTA RWEGANINSQ
     SALLDADDGA TVITDTIKDD QDDKEPKSCP QQTVKYIKIL TPHVILVSVL IGYLCLGAWI
     LMLLETRTEL LARSKKLVRL TNLMSNFTAE SWKMLNNAQH GVSNMDEGEW AATFREWMVR
     VSETVDDRRP IRRELNRPDD LSNMHNKWTF PTAILYVLTV LTTCGYGEVS VDTDVGKVFS
     VAFALVGIPL MFITAADIGK FLSETLLQFV SFWNRSVRKV KQWMSRIRHG RRKSLQSTGG
     PNDTLDILGV DGTEEKLWFP IGAYVSCICI YCSIGSAMFI TWERTWSFIH AFHFGFNLIV
     TVGLGDIVVT DYIFLSLIVA FVIVGLSVVT MCVDLASTHL KAYFTRIHYF GRAKRFLGMS
     EELKEIVALL GAMRRKKGGK VTWNDVRDFL DNELRDRPFE PHELLMKLRF IDETSSGMST
     IRHNSFQSDF FRESEYIRRV AALRPEQPAY L
//