ID A0A4V3T127_9ACTN Unreviewed; 546 AA.
AC A0A4V3T127;
DT 31-JUL-2019, integrated into UniProtKB/TrEMBL.
DT 31-JUL-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=E6R62_29065 {ECO:0000313|EMBL:THA48666.1};
OS Streptomyces sp. A1136.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2563102 {ECO:0000313|EMBL:THA48666.1, ECO:0000313|Proteomes:UP000307332};
RN [1] {ECO:0000313|EMBL:THA48666.1, ECO:0000313|Proteomes:UP000307332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1136 {ECO:0000313|EMBL:THA48666.1,
RC ECO:0000313|Proteomes:UP000307332};
RA Park C., Northup D., Sevigny J., Andam C.;
RT "Genome Sequencing and Assembly of Various Streptomyces sp. Isolated from
RT Bat Fecal Material.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:THA48666.1}.
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DR EMBL; SSBJ01000036; THA48666.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A4V3T127; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000307332; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000307332}.
FT DOMAIN 3..346
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 384..535
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 546 AA; 56016 MW; 7FE0B6E783AE4EE3 CRC64;
MSLAEKVGQL FVSRAYGHSA TAPDPADARL NQAQFGVRTA AELVARYHLG GVIYFAWAHN
TRTPGQIAAL SQELQLAAAG SGAGVPLLLS TDQEHGAVAR IGKPATLLPG AMALGAGHRA
TGSTAEARRA ARIAGAELAA MGIRQDYAPV ADVNVNPANP VIGVRSFGSD PRAVAALVAA
QVRGYQGAGV AATAKHFPGH GDTETDSHVG LPLMRHTRAQ WEELDEPPFR AAVAAGVDAV
MTAHIVFPAL DPSGDPATLS RPIVTGILRE RLGFGGVVVT DALDMAGVRQ KYGDDRVPVL
ALKAGCDQLL NPPDLALAYR SVLAAVESGE LTTARIEESV LRVLELKARR VLFAGPYTAG
PDLAEVGAAD HLTAADEIAA GTTTLLANPA GLLPLDASAA PRVLVTGAAP PSPSGTTGPP
TEVLARELAA LGCRASAVAP EGAPAAAPGH AAVLVCTYNV PEGDSPQRSL VADLLATGVP
VVAVAIRNPY DGARLPRCAA EVATYSWTDV EMRAAARVIT GARRPSGRLP VPVPGRYPLG
HGLTYD
//
